PMID- 17967589
OWN - NLM
STAT- MEDLINE
DCOM- 20071113
LR  - 20071030
IS  - 1097-6744 (Electronic)
IS  - 0002-8703 (Linking)
VI  - 154
IP  - 5
DP  - 2007 Nov
TI  - Effect of pulmonary stenosis on pregnancy outcomes--a case-control study.
PG  - 852-4
AB  - BACKGROUND: Pulmonary stenosis (PS) accounts for 10% to 12% of congenital heart 
      disease in adults, and the probability of survival to child bearing age is high. 
      The impact of PS on pregnancy has not been extensively studied in the recent era. 
      METHODS: We evaluate the effect of isolated PS on maternal and fetal outcomes in 
      a case-control study of 17 cases with PS in pregnancy from 1995 to 2006. The 
      control group was matched by age, ethnicity, obstetrical history, and year of 
      delivery. Patients with PS were assessed for maternal New York Heart Association 
      (NYHA) functional class and other maternal complications at baseline and during 
      pregnancy; and the 2 groups were compared for fetal and neonatal outcomes 
      including birth weight, gestational age at delivery, Apgar scores, and placental 
      weight. RESULTS: A total of 11 patients were in NYHA functional class I and 6 in 
      class II at the time of presentation. All patients remained stable during 
      pregnancy except for two. One of them deteriorated from NYHA functional class I 
      to II, and the other from class II transiently to class III. There were no other 
      maternal complications. In addition, there were no statistically significant 
      differences in fetal/neonatal outcomes between patients and their controls and 
      between patients with mild and severe PS. CONCLUSIONS: In contrast to mitral and 
      aortic stenosis, PS does not adversely impact maternal or fetal outcomes of 
      pregnancy.
FAU - Hameed, Afshan B
AU  - Hameed AB
AD  - Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, 
      University of California, Irvine, CA, USA.
FAU - Goodwin, Thomas Murphy
AU  - Goodwin TM
FAU - Elkayam, Uri
AU  - Elkayam U
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20070906
PL  - United States
TA  - Am Heart J
JT  - American heart journal
JID - 0370465
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Birth Weight
MH  - Female
MH  - Gestational Age
MH  - Humans
MH  - Infant, Newborn
MH  - Pregnancy
MH  - Pregnancy Complications, Cardiovascular/*epidemiology
MH  - Pregnancy Outcome
MH  - Pregnancy, High-Risk
MH  - Prevalence
MH  - Pulmonary Valve Stenosis/*epidemiology
MH  - Retrospective Studies
MH  - Risk Factors
MH  - United States/epidemiology
EDAT- 2007/10/31 09:00
MHDA- 2007/11/14 09:00
CRDT- 2007/10/31 09:00
PHST- 2007/01/29 00:00 [received]
PHST- 2007/07/30 00:00 [accepted]
PHST- 2007/10/31 09:00 [pubmed]
PHST- 2007/11/14 09:00 [medline]
PHST- 2007/10/31 09:00 [entrez]
AID - S0002-8703(07)00598-4 [pii]
AID - 10.1016/j.ahj.2007.07.016 [doi]
PST - ppublish
SO  - Am Heart J. 2007 Nov;154(5):852-4. doi: 10.1016/j.ahj.2007.07.016. Epub 2007 Sep 
      6.