PMID- 17969820
OWN - NLM
STAT- MEDLINE
DCOM- 20080110
LR  - 20190917
IS  - 0042-8450 (Print)
IS  - 0042-8450 (Linking)
VI  - 64
IP  - 9
DP  - 2007 Sep
TI  - [Ecstasy tablets intoxication with lethal autcome].
PG  - 635-8
AB  - BACKGROUND: Ecstasy, 3,4-methylenedioxymethamphetamine (MDMA), is a synthetic 
      compound increasingly popular as a recreational drug. Tablets known as ecstasy 
      contain MDMA, but may also contain caffeine, ephedrine, paramethoxyamphetamine, 
      3,4-methylenedioxyamphetamine (MDA), amphetamine, methamphetamine, and ketamine. 
      After absorption MDMA is metabolized to MDA, 4-hydroxy-3-metoxymetamphetamine 
      (HMMA) and 4-hydroxy-3-metoxyamphetamine (HMA). After that HMMA and HMA are 
      conjugated and excreted by urine. The aim of this report was to confirm by 
      toxicological post mortem analyses of poisoned person organs that ecstasy had 
      been the cause of his death. CASE REPORT: We reported the death of a 17-year-old 
      boy after the ingestion of ecstasy. MDMA and metabolites were determined by 
      multicolumn high performance liquid chromatography with UV spectral detection 
      (HPLC-UV). Toxicological tests showed the presence of MDMA in all samples. When 
      examining post mortem material (the organs), the highest concentrations were 
      measured in the stomach (835,97 microg/g) and kidney (801,14 microg/g). The 
      minimal concentration was in the liver (22,26 microg/g). CONCLUSION: The obtained 
      results of MDMA and its metabolites concentrations showed abuse of a high dose of 
      ecstasy.
FAU - Dordevic, Snezana
AU  - Dordevic S
AD  - Vojnomedicinska akademija, Centar za kontrolu trovanja, Beograd, Srbija.
FAU - Tomasevic, Gordana
AU  - Tomasevic G
LA  - srp
PT  - Case Reports
PT  - English Abstract
PT  - Journal Article
PL  - Serbia
TA  - Vojnosanit Pregl
JT  - Vojnosanitetski pregled
JID - 21530700R
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adolescent
MH  - Fatal Outcome
MH  - Hallucinogens/*poisoning
MH  - Humans
MH  - Male
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*poisoning
MH  - Substance Abuse Detection
EDAT- 2007/11/01 09:00
MHDA- 2008/01/11 09:00
CRDT- 2007/11/01 09:00
PHST- 2007/11/01 09:00 [pubmed]
PHST- 2008/01/11 09:00 [medline]
PHST- 2007/11/01 09:00 [entrez]
AID - 10.2298/vsp0709635d [doi]
PST - ppublish
SO  - Vojnosanit Pregl. 2007 Sep;64(9):635-8. doi: 10.2298/vsp0709635d.