PMID- 17972226
OWN - NLM
STAT- MEDLINE
DCOM- 20071219
LR  - 20071031
IS  - 0927-3948 (Print)
IS  - 0927-3948 (Linking)
VI  - 15
IP  - 5
DP  - 2007 Sep-Oct
TI  - Recurrent multi-organism keratoconjunctivitis manifesting as a first presentation 
      of common variable immune deficiency (CVID).
PG  - 403-5
AB  - Common variable immune deficiency (CVID) is characterized by 
      hypogammaglobulinemia, impaired antibody production, and recurrent bacterial 
      infections. Reports of ocular manifestations of CVID are rare. The authors 
      discuss a patient with recurrent keratoconjunctivitis that presented as an 
      initial manifestation of CVID. The diagnosis of CVID should be entertained where 
      multiple recurrences of keratoconjunctivitis are unresponsive to antibiotic and 
      steroid therapy and when other causes of immune deficiency have been excluded. 
      Intravenous immunoglobulin (IVIG) was used successfully as treatment and is 
      required lifelong as prophylaxis against further episodes of keratoconjunctivitis 
      as well as the other infectious and inflammatory complications of this primary 
      immunodeficiency syndrome.
FAU - Ooi, Kenneth G-J
AU  - Ooi KG
AD  - Bathurst Eye Clinic, Bathurst, New South Wales, Australia. kgjooi@yahoo.com.au
FAU - Joshua, Fredrick
AU  - Joshua F
FAU - Broadfoot, Andrew
AU  - Broadfoot A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Ocul Immunol Inflamm
JT  - Ocular immunology and inflammation
JID - 9312169
RN  - 0 (Immunoglobulins, Intravenous)
SB  - IM
MH  - Adult
MH  - Bacterial Infections/*etiology
MH  - Common Variable Immunodeficiency/*complications/drug therapy/prevention & control
MH  - Drug Administration Schedule
MH  - Humans
MH  - Immunoglobulins, Intravenous/administration & dosage/therapeutic use
MH  - Keratoconjunctivitis/*etiology/microbiology
MH  - Male
MH  - Recurrence
EDAT- 2007/11/01 09:00
MHDA- 2007/12/20 09:00
CRDT- 2007/11/01 09:00
PHST- 2007/11/01 09:00 [pubmed]
PHST- 2007/12/20 09:00 [medline]
PHST- 2007/11/01 09:00 [entrez]
AID - 783648339 [pii]
AID - 10.1080/09273940701486449 [doi]
PST - ppublish
SO  - Ocul Immunol Inflamm. 2007 Sep-Oct;15(5):403-5. doi: 10.1080/09273940701486449.