PMID- 17975321
OWN - NLM
STAT- MEDLINE
DCOM- 20080422
LR  - 20080227
IS  - 1423-0100 (Electronic)
IS  - 0300-5526 (Linking)
VI  - 50
IP  - 6
DP  - 2007
TI  - Mouse mammary tumor virus-like gene sequences in breast cancer samples of Mexican 
      women.
PG  - 402-7
AB  - BACKGROUND: Previous reports related the presence of mouse mammary tumor virus 
      (MMTV)-like gene sequences to human breast carcinoma. The aim of this study was 
      to determine whether MMTV-like env gene sequences are present in breast cancer 
      samples of Mexican women and in breast and lung cancer cell lines. METHODS: Using 
      specific primers for MMTV, we tested 3 breast cancer cell lines, 4 non-small lung 
      cancer cell lines and 119 breast cancer samples from Mexican women. RESULTS: 
      MMTV-like gene sequences were amplified in the lung cancer cell INER-51, but not 
      in the MCF-7 cell line that has been used as a positive control in other reports 
      and in 5 of 119 (4.2%) breast cancer biopsy tissues. Furthermore, the identity of 
      sequences of PCR products from INER-51 and a breast cancer-positive sample are 98 
      and 99% when compared with the env region of MMTV (GenBank accession No. 
      AY161347). CONCLUSION: These results indicate that MMTV-like gene sequences are 
      present in the Mexican population.
CI  - (c) 2007 S. Karger AG, Basel
FAU - Zapata-Benavides, P
AU  - Zapata-Benavides P
AD  - Departamento de Microbiologia e Inmunologia, Facultad de Ciencias Biologicas, 
      Universidad Autonoma de Nuevo Leon (UANL), Ciudad Universitaria, San Nicolas de 
      los Garza, NL, Mexico.
FAU - Saavedra-Alonso, S
AU  - Saavedra-Alonso S
FAU - Zamora-Avila, D
AU  - Zamora-Avila D
FAU - Vargas-Rodarte, C
AU  - Vargas-Rodarte C
FAU - Barrera-Rodriguez, R
AU  - Barrera-Rodriguez R
FAU - Salinas-Silva, J
AU  - Salinas-Silva J
FAU - Rodriguez-Padilla, C
AU  - Rodriguez-Padilla C
FAU - Tamez-Guerra, R
AU  - Tamez-Guerra R
FAU - Trejo-Avila, L
AU  - Trejo-Avila L
LA  - eng
SI  - GENBANK/AY161347
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071031
PL  - Switzerland
TA  - Intervirology
JT  - Intervirology
JID - 0364265
RN  - 0 (DNA Primers)
RN  - 0 (DNA, Neoplasm)
SB  - IM
MH  - Breast Neoplasms/pathology/*virology
MH  - Cell Line
MH  - DNA Primers
MH  - DNA, Neoplasm/analysis
MH  - Female
MH  - *Genes, env
MH  - Humans
MH  - Mammary Tumor Virus, Mouse/*genetics/*isolation & purification
MH  - Mexico
MH  - Molecular Sequence Data
EDAT- 2007/11/03 09:00
MHDA- 2008/04/23 09:00
CRDT- 2007/11/03 09:00
PHST- 2007/03/19 00:00 [received]
PHST- 2007/08/08 00:00 [accepted]
PHST- 2007/11/03 09:00 [pubmed]
PHST- 2008/04/23 09:00 [medline]
PHST- 2007/11/03 09:00 [entrez]
AID - 000110652 [pii]
AID - 10.1159/000110652 [doi]
PST - ppublish
SO  - Intervirology. 2007;50(6):402-7. doi: 10.1159/000110652. Epub 2007 Oct 31.