PMID- 17981706
OWN - NLM
STAT- MEDLINE
DCOM- 20071211
LR  - 20190902
IS  - 1093-9946 (Print)
IS  - 1093-4715 (Linking)
VI  - 13
DP  - 2008 Jan 1
TI  - The role of chemokines and their receptors in dendritic cell biology.
PG  - 2238-52
AB  - Dendritic cells (DCs) are the chief inducers of adaptive immunity. Their normal 
      life cycle begins with the generation of their precursors in the bone-marrow, 
      followed by their release into the blood stream, continues with their entry into 
      non-lymphoid tissues and commences with steady-state or infection-induced 
      migration into draining lymph nodes. Each of these migration steps is controlled 
      by distinct chemokine-chemokine receptor interactions, facilitated by dynamic 
      changes in chemokine receptor expression. In this review, we describe current 
      knowledge on the role of chemokines and their receptors in the control of DC 
      migratory behavior, as well as other influences on DC biology.
FAU - Lukacs-Kornek, Veronika
AU  - Lukacs-Kornek V
AD  - Institute for Molecular Medicine and Experimental Immunology, University of Bonn, 
      Germany.
FAU - Engel, Daniel
AU  - Engel D
FAU - Tacke, Frank
AU  - Tacke F
FAU - Kurts, Christian
AU  - Kurts C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20080101
PL  - United States
TA  - Front Biosci
JT  - Frontiers in bioscience : a journal and virtual library
JID - 9709506
RN  - 0 (Chemokines)
RN  - 0 (Receptors, Interleukin-8A)
SB  - IM
MH  - Animals
MH  - Cell Differentiation
MH  - Cell Lineage
MH  - Cell Movement
MH  - Chemokines/*metabolism
MH  - Dendritic Cells/*cytology/metabolism
MH  - Endocytosis
MH  - Humans
MH  - Immunity, Innate
MH  - Lymphocyte Activation
MH  - Mice
MH  - Models, Biological
MH  - Monocytes/metabolism
MH  - Receptors, Interleukin-8A/metabolism
MH  - T-Lymphocytes/metabolism
RF  - 150
EDAT- 2007/11/06 09:00
MHDA- 2007/12/12 09:00
CRDT- 2007/11/06 09:00
PHST- 2007/11/06 09:00 [pubmed]
PHST- 2007/12/12 09:00 [medline]
PHST- 2007/11/06 09:00 [entrez]
AID - 2838 [pii]
AID - 10.2741/2838 [doi]
PST - epublish
SO  - Front Biosci. 2008 Jan 1;13:2238-52. doi: 10.2741/2838.