PMID- 17985096
OWN - NLM
STAT- MEDLINE
DCOM- 20080304
LR  - 20220716
IS  - 0043-5325 (Print)
IS  - 0043-5325 (Linking)
VI  - 119
IP  - 19-20
DP  - 2007
TI  - Surgical aspects of gastrinoma in multiple endocrine neoplasia type 1.
PG  - 602-8
AB  - Gastrinoma is the most frequent functional pancreaticoduodenal endocrine tumor in 
      patients with multiple endocrine neoplasia type 1 (MEN1) and one major 
      determinant of mortality in this syndrome. Whether routine surgical exploration 
      should be performed in a patient with MEN1 associated Zollinger-Ellison syndrome 
      (ZES) to possibly reduce the malignant spread and eventually increase survival 
      still remains controversial. There is not only disagreement about the indication 
      for surgical exploration, but also what type of procedure should be performed, 
      since sufficient evidence-based data are not available. The article discusses the 
      available data on treatment strategies of MEN1 associated ZES.
FAU - Bartsch, Detlef K
AU  - Bartsch DK
AD  - Klinik fur Allgemein- und Viszeralchirurgie der Stadt. Kliniken Bielefeld-Mitte, 
      Bielefeld, Germany. bartsch.detlef@sk-bielefeld.de
FAU - Langer, Peter
AU  - Langer P
FAU - Rothmund, Matthias
AU  - Rothmund M
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Austria
TA  - Wien Klin Wochenschr
JT  - Wiener klinische Wochenschrift
JID - 21620870R
RN  - 0 (Gastrins)
SB  - IM
MH  - Disease Progression
MH  - Duodenal Neoplasms/blood/mortality/*surgery
MH  - Gastrinoma/blood/mortality/*surgery
MH  - Gastrins/*blood
MH  - Humans
MH  - Laparoscopy
MH  - Multiple Endocrine Neoplasia Type 1/blood/mortality/*surgery
MH  - Pancreatectomy
MH  - Pancreatic Neoplasms/blood/mortality/*surgery
MH  - Pancreaticoduodenectomy
MH  - Prognosis
MH  - Reoperation
MH  - Survival Rate
MH  - Zollinger-Ellison Syndrome/blood/mortality/surgery
RF  - 65
EDAT- 2007/11/07 09:00
MHDA- 2008/03/05 09:00
CRDT- 2007/11/07 09:00
PHST- 2007/11/07 09:00 [pubmed]
PHST- 2008/03/05 09:00 [medline]
PHST- 2007/11/07 09:00 [entrez]
AID - 10.1007/s00508-007-0883-3 [doi]
PST - ppublish
SO  - Wien Klin Wochenschr. 2007;119(19-20):602-8. doi: 10.1007/s00508-007-0883-3.