PMID- 17985568
OWN - NLM
STAT- MEDLINE
DCOM- 20071211
LR  - 20190917
IS  - 0065-1419 (Print)
IS  - 0065-1419 (Linking)
VI  - 100
DP  - 2007
TI  - In peripheral nerve regeneration environment enriched with activity stimulating 
      factors improves functional recovery.
PG  - 161-7
AB  - Enriched environment stimulates brain plasticity processes after brain lesion. 
      Less is known about the influence of enriched environment with activity 
      stimulating factors as determinants of functional outcome after peripheral nerve 
      repair. BDNF (brain-derived neurotrophic factor) plays a role in 
      activity-dependent neuronal plasticity and changes in motor cortex in rats 
      learning complex motor skills. Our study aimed to elucidate if enriched 
      environment influences functional results after peripheral nerve repair. The 
      results in this rat sciatic nerve transection and repair model showed that 
      environment enriched with activity stimulating factors can improve functional 
      results.
FAU - Schmidhammer, R
AU  - Schmidhammer R
AD  - Austrian Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Clinical 
      and Experimental Traumatology, Research Center of the AUVA, Vienna, Austria. 
      r.schmidhammer@gmx.de
FAU - Hausner, T
AU  - Hausner T
FAU - Hopf, R
AU  - Hopf R
FAU - Zandieh, S
AU  - Zandieh S
FAU - Redl, H
AU  - Redl H
LA  - eng
PT  - Journal Article
PL  - Austria
TA  - Acta Neurochir Suppl
JT  - Acta neurochirurgica. Supplement
JID - 100962752
RN  - 0 (Brain-Derived Neurotrophic Factor)
SB  - IM
MH  - Action Potentials
MH  - Animals
MH  - Brain-Derived Neurotrophic Factor/metabolism
MH  - Electromyography
MH  - *Environment
MH  - Enzyme-Linked Immunosorbent Assay
MH  - Hindlimb/physiopathology
MH  - Male
MH  - Motor Activity
MH  - Motor Cortex/metabolism
MH  - Muscle, Skeletal/pathology/physiopathology
MH  - *Nerve Regeneration
MH  - Neural Conduction
MH  - Proprioception
MH  - Rats
MH  - Rats, Sprague-Dawley
MH  - Reaction Time
MH  - *Recovery of Function
MH  - Sciatic Nerve/*injuries/*physiopathology
MH  - Somatosensory Cortex/metabolism
MH  - Toes/physiopathology
MH  - Trauma, Nervous System/metabolism/physiopathology
EDAT- 2007/11/08 09:00
MHDA- 2007/12/12 09:00
CRDT- 2007/11/08 09:00
PHST- 2007/11/08 09:00 [pubmed]
PHST- 2007/12/12 09:00 [medline]
PHST- 2007/11/08 09:00 [entrez]
AID - 10.1007/978-3-211-72958-8_34 [doi]
PST - ppublish
SO  - Acta Neurochir Suppl. 2007;100:161-7. doi: 10.1007/978-3-211-72958-8_34.