PMID- 17986354
OWN - NLM
STAT- MEDLINE
DCOM- 20080124
LR  - 20240414
IS  - 1475-2891 (Electronic)
IS  - 1475-2891 (Linking)
VI  - 6
DP  - 2007 Nov 6
TI  - Diagnostic criteria patterns of U.S. children with Metabolic Syndrome: NHANES 
      1999-2002.
PG  - 38
AB  - BACKGROUND: As childhood obesity increases in the U.S., the Metabolic Syndrome 
      (MS) can be assumed to be increasing in the pediatric population as well. To 
      date, there is lack of information on the most prevalent risk factors of MS in 
      children and the patterns of risk factors present in children met the criteria 
      for MS. METHODS: Anthropometric and medical data of children 2-18 years old of a 
      nationally representative data set (NHANES 1999-2002) were obtained and the 
      diagnostic criteria of Cook et al. employed to determine MS prevalence. Three 
      samples were examined: a) Children 2-18 years old with non-missing data on at 
      least three of the five diagnostic criteria but missing blood glucose data (n = 
      5,172), b) a subsample of 12-18 year olds also providing fasting glucose data but 
      who were not overweight or obese using the International Obesity Task Force 
      (IOTF) standards (n = 1,064), and c) 12-18 year olds with blood glucose data who 
      were overweight or obese (n = 641). RESULTS: Disease prevalence estimates were 
      2%, 0.7%, and 23% in the three populations. More than 10% of the children 
      providing fasting blood levels had hyperglycemia. 2% of the overweight or obese 
      12-18 year olds with fasting blood glucose data met all five diagnostic criteria 
      for MS. In all groups, elevated total triglycerides but low high density 
      lipoprotein (HDL) level affected a large proportion of the population. 
      CONCLUSION: Results indicate a reason for concern, since the prevalence of MS 
      risk factors in children was high. Dyslipidemia (concurrent high total 
      triglyceride levels and low HDL levels) were prevalent in large portions of the 
      population, even in the non-overweight. Thus, chronic disease prevention efforts 
      in the pediatric population should not only encourage healthy body weight but 
      also include dietary recommendations to consume diets moderately low in fat with 
      emphasis on polyunsaturated and monounsaturated fats within recommended ratios of 
      omega-6 and omega-3 fatty acids.
FAU - Kranz, Sibylle
AU  - Kranz S
AD  - Department of Nutritional Sciences, The Pennsylvania State University, 5 
      Henderson Building, University Park, PA 16802, USA. sxk72@psu.edu
FAU - Mahood, Lindsey J
AU  - Mahood LJ
FAU - Wagstaff, David A
AU  - Wagstaff DA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20071106
PL  - England
TA  - Nutr J
JT  - Nutrition journal
JID - 101152213
RN  - 0 (Lipoproteins, HDL)
RN  - 0 (Oligosaccharides)
RN  - 0 (Triglycerides)
RN  - 99147-61-2 (blood group A active hexaglycosylceramide type 2 chain)
SB  - IM
MH  - Abdomen
MH  - Adolescent
MH  - Anthropometry
MH  - Body Mass Index
MH  - Body Weight
MH  - Child
MH  - Child, Preschool
MH  - Fasting
MH  - Female
MH  - Humans
MH  - Hyperglycemia/diagnosis/epidemiology
MH  - Lipoproteins, HDL/blood
MH  - Male
MH  - Metabolic Syndrome/*diagnosis/epidemiology
MH  - Nutrition Surveys
MH  - Obesity/epidemiology
MH  - Oligosaccharides
MH  - Risk Factors
MH  - Triglycerides/blood
MH  - United States/epidemiology
PMC - PMC2194729
EDAT- 2007/11/08 09:00
MHDA- 2008/01/25 09:00
PMCR- 2007/11/06
CRDT- 2007/11/08 09:00
PHST- 2007/06/15 00:00 [received]
PHST- 2007/11/06 00:00 [accepted]
PHST- 2007/11/08 09:00 [pubmed]
PHST- 2008/01/25 09:00 [medline]
PHST- 2007/11/08 09:00 [entrez]
PHST- 2007/11/06 00:00 [pmc-release]
AID - 1475-2891-6-38 [pii]
AID - 10.1186/1475-2891-6-38 [doi]
PST - epublish
SO  - Nutr J. 2007 Nov 6;6:38. doi: 10.1186/1475-2891-6-38.