PMID- 17990052
OWN - NLM
STAT- MEDLINE
DCOM- 20080331
LR  - 20211020
IS  - 0940-1334 (Print)
IS  - 0940-1334 (Linking)
VI  - 258
IP  - 1
DP  - 2008 Feb
TI  - Prediction of community outcome in schizophrenia 1 year after discharge from 
      inpatient treatment.
PG  - 48-58
AB  - This longitudinal study aimed at identifying predictors of community outcome from 
      a broad range of neuropsychological, clinical psychopathologic, sociodemographic, 
      and treatment related factors. N = 96 schizophrenia patients were assessed both 
      at baseline during inpatient treatment and 1 year after discharge from hospital 
      (follow-up). At follow-up functional outcome was measured by the Global 
      Assessment of Functioning Scale (GAF) and the Social Adjustment Scale II (SAS 
      II). Data were analyzed in an explorative way by means of multiple linear 
      regression analyses. Three out of the five functional outcome measures were 
      predicted by the negative syndrome and measures of cognitive functioning. 
      However, the positive syndrome also consistently predicted psychosocial 
      functioning. Altogether, the regression models explained between 20% and 35% of 
      the variance in our outcome measures. The findings not only reemphasize that 
      negative symptoms and cognitive dysfunctions are key determinants of community 
      outcome but also point to a potential predictive relevance of positive symptoms.
FAU - Wittorf, Andreas
AU  - Wittorf A
AD  - Dept. of Psychiatry and Psychotherapy, University of Tuebingen, Osiander Str. 24, 
      72076, Tuebingen, Germany. andreas.wittorf@med.uni-tuebingen.de
FAU - Wiedemann, Georg
AU  - Wiedemann G
FAU - Buchkremer, Gerhard
AU  - Buchkremer G
FAU - Klingberg, Stefan
AU  - Klingberg S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071107
PL  - Germany
TA  - Eur Arch Psychiatry Clin Neurosci
JT  - European archives of psychiatry and clinical neuroscience
JID - 9103030
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Activities of Daily Living/psychology
MH  - Adaptation, Psychological
MH  - Adult
MH  - Antipsychotic Agents/therapeutic use
MH  - Cognitive Behavioral Therapy
MH  - Data Interpretation, Statistical
MH  - Employment
MH  - Female
MH  - Follow-Up Studies
MH  - Germany
MH  - Hospitalization
MH  - Humans
MH  - Inpatients
MH  - Linear Models
MH  - Longitudinal Studies
MH  - Male
MH  - Patient Discharge
MH  - Psychiatric Status Rating Scales
MH  - Schizophrenia/drug therapy/*therapy
MH  - *Schizophrenic Psychology
MH  - Secondary Prevention
MH  - Social Behavior
MH  - Socioeconomic Factors
MH  - Treatment Outcome
EDAT- 2007/11/09 09:00
MHDA- 2008/04/01 09:00
CRDT- 2007/11/09 09:00
PHST- 2007/04/03 00:00 [received]
PHST- 2007/09/03 00:00 [accepted]
PHST- 2007/11/09 09:00 [pubmed]
PHST- 2008/04/01 09:00 [medline]
PHST- 2007/11/09 09:00 [entrez]
AID - 10.1007/s00406-007-0761-z [doi]
PST - ppublish
SO  - Eur Arch Psychiatry Clin Neurosci. 2008 Feb;258(1):48-58. doi: 
      10.1007/s00406-007-0761-z. Epub 2007 Nov 7.