PMID- 17997840
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20121002
LR  - 20211020
IS  - 1550-2783 (Electronic)
IS  - 1550-2783 (Linking)
VI  - 4
DP  - 2007 Nov 12
TI  - Effects of ingesting protein with various forms of carbohydrate following 
      resistance-exercise on substrate availability and markers of anabolism, 
      catabolism, and immunity.
PG  - 18
LID - 10.1186/1550-2783-4-18 [doi]
AB  - BACKGROUND: Ingestion of carbohydrate (CHO) and protein (PRO) following intense 
      exercise has been reported to increase insulin levels, optimize glycogen 
      resynthesis, enhance PRO synthesis, and lessen the immuno-suppressive effects of 
      intense exercise. Since different forms of CHO have varying glycemic effects, the 
      purpose of this study was to determine whether the type of CHO ingested with PRO 
      following resistance-exercise affects blood glucose availability and insulin 
      levels, markers of anabolism and catabolism, and/or general immune markers. 
      METHODS: 40 resistance-trained subjects performed a standardized resistance 
      training workout and then ingested in a double blind and randomized manner 40 g 
      of whey PRO with 120 g of sucrose (S), honey powder (H), or maltodextrin (M). A 
      non-supplemented control group (C) was also evaluated. Blood samples were 
      collected prior to and following exercise as well as 30, 60, 90, and 120 min 
      after ingestion of the supplements. Data were analyzed by repeated measures ANOVA 
      or ANCOVA using baseline values as a covariate if necessary. RESULTS: Glucose 
      concentration 30 min following ingestion showed the H group (7.12 +/- 0.2 mmol/L) 
      to be greater than S (5.53 +/- 0.6 mmol/L; p < 0.03); M (6.02 +/- 0.8 mmol/L; p < 
      0.05), and C (5.44 +/- 0.18 mmol/L; p < 0.0002) groups. No significant 
      differences were observed among groups in glucose area under the curve (AUC) 
      values, although the H group showed a trend versus control (p = 0.06). Insulin 
      response for each treatment was significant by time (p < 0.0001), treatment (p < 
      0.0001) and AUC (p < 0.0001). 30-min peak post-feeding insulin for S (136.2 +/- 
      15.6 uIU/mL), H (150.1 +/- 25.39 uIU/mL), and M (154.8 +/- 18.9 uIU/mL) were 
      greater than C (8.7 +/- 2.9 uIU/mL) as was AUC with no significant differences 
      observed among types of CHO. No significant group x time effects were observed 
      among groups in testosterone, cortisol, the ratio of testosterone to cortisol, 
      muscle and liver enzymes, or general markers of immunity. CONCLUSION: CHO and PRO 
      ingestion following exercise significantly influences glucose and insulin 
      concentrations. Although some trends were observed suggesting that H maintained 
      blood glucose levels to a better degree, no significant differences were observed 
      among types of CHO ingested on insulin levels. These findings suggest that each 
      of these forms of CHO can serve as effective sources of CHO to ingest with PRO in 
      and attempt to promote post-exercise anabolic responses.
FAU - Kreider, Richard B
AU  - Kreider RB
AD  - Exercise & Sport Nutrition Lab, Center for Exercise, Nutrition and Preventive 
      Health, Baylor University, Waco, TX, USA.
FAU - Earnest, Conrad P
AU  - Earnest CP
AD  - Preventive Medicine Laboratory, Pennington Biomedical Research Center, Baton 
      Rouge, Louisiana, USA.
FAU - Lundberg, Jennifer
AU  - Lundberg J
AD  - St. Paul Heart Clinic, St. Paul, MN, USA.
FAU - Rasmussen, Christopher
AU  - Rasmussen C
AD  - Exercise & Sport Nutrition Lab, Center for Exercise, Nutrition and Preventive 
      Health, Baylor University, Waco, TX, USA.
FAU - Greenwood, Michael
AU  - Greenwood M
AD  - Exercise & Sport Nutrition Lab, Center for Exercise, Nutrition and Preventive 
      Health, Baylor University, Waco, TX, USA.
FAU - Cowan, Patricia
AU  - Cowan P
AD  - College of Nursing, University of Tennessee Medical School, Memphis, TN, USA.
FAU - Almada, Anthony L
AU  - Almada AL
AD  - ImagiNutrition, Inc., Laguna Niguel, CA, USA.
LA  - eng
PT  - Journal Article
DEP - 20071112
PL  - United States
TA  - J Int Soc Sports Nutr
JT  - Journal of the International Society of Sports Nutrition
JID - 101234168
PMC - PMC2206056
EDAT- 2007/11/14 09:00
MHDA- 2007/11/14 09:01
PMCR- 2007/11/12
CRDT- 2007/11/14 09:00
PHST- 2007/10/21 00:00 [received]
PHST- 2007/11/12 00:00 [accepted]
PHST- 2007/11/14 09:00 [pubmed]
PHST- 2007/11/14 09:01 [medline]
PHST- 2007/11/14 09:00 [entrez]
PHST- 2007/11/12 00:00 [pmc-release]
AID - 1550-2783-4-18 [pii]
AID - 10.1186/1550-2783-4-18 [doi]
PST - epublish
SO  - J Int Soc Sports Nutr. 2007 Nov 12;4:18. doi: 10.1186/1550-2783-4-18.