PMID- 17998592
OWN - NLM
STAT- MEDLINE
DCOM- 20080128
LR  - 20211020
IS  - 1234-1983 (Print)
IS  - 1234-1983 (Linking)
VI  - 48
IP  - 4
DP  - 2007
TI  - Clastogenic and mitodepressive effects of the insecticide dichlorvos on root 
      meristems of Vicia faba.
PG  - 359-61
AB  - Plant bioassays are an important and integral part of the test battery used in 
      detecting genotoxic/carcinogenic contamination in the environment. Highly 
      sensitive biomonitoring of plant models have been developed, which enables the 
      detection of hazards arising from pesticides, insecticides, industrial 
      contamination, heavy metals and radiation. Root tips of Vicia faba ssp. minor 
      were treated with 1-60 mM of the organophosphorus insecticide dichlorvos (DDVP) 
      for 2 h, followed by a 20-h recovery period. Maleic acid hydrazide (MH) was used 
      as a positive control for the mitotic index, micronucleus and chromosomal 
      aberration assays performed on the Vicia model system. All treatments with DDVP 
      significantly decreased the mitotic activity and increased the frequency of 
      chromosomal aberrations at the metaphase. The frequency of micronuclei was 
      significantly increased at DDVP concentrations starting from 10 mM. The results 
      demonstrate clastogenic and mitodepressive effects of DDVP on Vicia faba cells.
FAU - Kontek, Renata
AU  - Kontek R
AD  - Laboratory of Cytogenetics, Department of General Genetics, Molecular Biology and 
      Plant Biotechnology, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. 
      renkon@biol.uni.lodz.pl
FAU - Osiecka, Regina
AU  - Osiecka R
FAU - Kontek, Bodgan
AU  - Kontek B
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Appl Genet
JT  - Journal of applied genetics
JID - 9514582
RN  - 0 (Insecticides)
RN  - 0 (Mutagens)
RN  - 7U370BPS14 (Dichlorvos)
SB  - IM
MH  - Chromosome Aberrations
MH  - Dichlorvos/*toxicity
MH  - Insecticides/*toxicity
MH  - Meristem/*drug effects/genetics
MH  - Micronuclei, Chromosome-Defective
MH  - Mitotic Index
MH  - Mutagens/toxicity
MH  - Plant Roots/*drug effects/genetics
MH  - Vicia faba/*drug effects/*genetics/physiology
EDAT- 2007/11/14 09:00
MHDA- 2008/01/29 09:00
CRDT- 2007/11/14 09:00
PHST- 2007/11/14 09:00 [pubmed]
PHST- 2008/01/29 09:00 [medline]
PHST- 2007/11/14 09:00 [entrez]
AID - 413 [pii]
AID - 10.1007/BF03195232 [doi]
PST - ppublish
SO  - J Appl Genet. 2007;48(4):359-61. doi: 10.1007/BF03195232.