PMID- 18007401
OWN - NLM
STAT- MEDLINE
DCOM- 20080205
LR  - 20211020
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 11
IP  - 12
DP  - 2006 Dec 18
TI  - Hyperbranched molecular structures with potential antiviral activity: derivatives 
      of 5,6-dihydroxyindole-2-carboxylic Acid.
PG  - 968-77
AB  - In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of 
      multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary 
      results indicate that hyperbranched architectures could represent a peculiar 
      molecular requisite for the development of new antiviral lead compounds.
FAU - Sechi, Mario
AU  - Sechi M
AD  - Dipartimento Farmaco Chimico Tossicologico, Universita di Sassari, Via Muroni 
      23/A, 07100 Sassari, Italy. mario.sechi@uniss.it
FAU - Casu, Fabio
AU  - Casu F
FAU - Campesi, Ilaria
AU  - Campesi I
FAU - Fiori, Stefano
AU  - Fiori S
FAU - Mariani, Alberto
AU  - Mariani A
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20061218
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Antiviral Agents)
RN  - 0 (Indoles)
RN  - 4790-08-3 (5,6-dihydroxy-2-indolylcarboxylic acid)
SB  - IM
MH  - Antiviral Agents/*chemistry/*pharmacology
MH  - Cell Line
MH  - HIV-1/drug effects
MH  - Humans
MH  - Indoles/*chemistry/*pharmacology
MH  - Microbial Sensitivity Tests
PMC - PMC6148522
EDAT- 2007/11/17 09:00
MHDA- 2008/02/06 09:00
PMCR- 2006/12/18
CRDT- 2007/11/17 09:00
PHST- 2006/10/25 00:00 [received]
PHST- 2006/12/08 00:00 [revised]
PHST- 2006/12/15 00:00 [accepted]
PHST- 2007/11/17 09:00 [pubmed]
PHST- 2008/02/06 09:00 [medline]
PHST- 2007/11/17 09:00 [entrez]
PHST- 2006/12/18 00:00 [pmc-release]
AID - 11120968 [pii]
AID - molecules-11-00968 [pii]
AID - 10.3390/11120968 [doi]
PST - epublish
SO  - Molecules. 2006 Dec 18;11(12):968-77. doi: 10.3390/11120968.