PMID- 18022404
OWN - NLM
STAT- MEDLINE
DCOM- 20071219
LR  - 20071120
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 605
IP  - 1
DP  - 2007 Dec 12
TI  - Preparation of a high pH-resistant AAPTS-silica coating and its application to 
      capillary microextraction (CME) of Cu, Zn, Ni, Hg and Cd from biological samples 
      followed by on-line ICP-MS detection.
PG  - 1-10
AB  - In this work, a novel sol-gel coating of 
      N-(2-aminoethyl)-3-aminopropyltrimethoxysilane (AAPTS)-silica was prepared for 
      capillary microextraction (CME) of trace Cu, Zn, Ni, Hg and Cd followed by 
      on-line ICP-MS detection. This organic-inorganic hybrid coating was in situ 
      created on the inner walls of fused silica capillary using a sol solution 
      containing tetramethoxysilane (TMOS) as a precursor, AAPTS as a co-precursor, 
      ethanol as the solvent and cetyltrimethylammonium bromide (CTAB) as the template. 
      The structure of the capillary coating was characterized by IR, SEM and TEM. 
      Various experimental parameters affecting capillary microextraction of the target 
      analytes have been investigated carefully, and the optimized extraction 
      conditions were established. It was found that the AAPTS-silica coating with a 
      terminal functional group of -NH-CH2-CH2-NH2 exhibited a high selectivity towards 
      the selected metal ions. With a consumption of 1.0 mL sample solution and 80 
      microL eluent, the detection limits (3sigma) were found to be 1.8, 11.8, 1.1, 3.3 
      and 1.4 pg mL(-1) for Cu, Zn, Ni, Hg and Cd, respectively. A sampling frequency 
      of 14 h(-1) and an enrichment factor of 12.5 were obtained under the optimized 
      experimental conditions. The relative standard deviations (RSDs) for the target 
      analytes were less than 3.6% (C = 1 ng mL(-1), n = 7, sample volume = 1 mL). Two 
      certified reference materials of NIES No.10-c rice flour and BCR-CRM 278 mussel 
      flesh were analyzed to validate the proposed method, and the determined values 
      were in good agreement with the certified values. The developed method had also 
      been applied to the determination of trace target elements in human hair, serum 
      and urine, and the recoveries for the spiked samples were in the range of 
      89.2-101.8%. The AAPTS-silica coated capillary showed an excellent pH resistance 
      and could be used for more than 120 times without decreasing adsorption 
      efficiency.
FAU - Zheng, Fei
AU  - Zheng F
AD  - Department of Chemistry, Wuhan University, Wuhan 430072, PR China.
FAU - Hu, Bin
AU  - Hu B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071022
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Metals, Heavy)
RN  - 0 (Propylamines)
RN  - 0 (Silanes)
RN  - 13822-56-5 (3-aminopropyltrimethoxysilane)
RN  - 7631-86-9 (Silicon Dioxide)
SB  - IM
MH  - Gas Chromatography-Mass Spectrometry
MH  - Hair/*chemistry
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Metals, Heavy/*blood/chemistry/*urine
MH  - Propylamines/*chemistry
MH  - Silanes/*chemistry
MH  - Silicon Dioxide/*chemistry
MH  - Solid Phase Microextraction/*methods
MH  - Surface Properties
EDAT- 2007/11/21 09:00
MHDA- 2007/12/20 09:00
CRDT- 2007/11/21 09:00
PHST- 2007/08/08 00:00 [received]
PHST- 2007/10/12 00:00 [revised]
PHST- 2007/10/12 00:00 [accepted]
PHST- 2007/11/21 09:00 [pubmed]
PHST- 2007/12/20 09:00 [medline]
PHST- 2007/11/21 09:00 [entrez]
AID - S0003-2670(07)01724-2 [pii]
AID - 10.1016/j.aca.2007.10.018 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2007 Dec 12;605(1):1-10. doi: 10.1016/j.aca.2007.10.018. Epub 
      2007 Oct 22.