PMID- 18026634 OWN - NLM STAT- MEDLINE DCOM- 20080515 LR - 20190608 IS - 0036-4665 (Print) IS - 0036-4665 (Linking) VI - 49 IP - 5 DP - 2007 Sep-Oct TI - Expression of circulating leucocytes before, during and after myiasis by Dermatobia hominis in experimentally infected rats. PG - 289-92 AB - Expression of circulating white blood cells was investigated in rats (Rattus norvegicus) experimentally infected with larvae of Dermatobia hominis, the human bot fly. Leucocytes were counted prior to infection (control group) as well as at 6, 10, 15, 20 and 28 days post-infection (dpi) and at 7, 15, 30 and 60 days post-larval emergence (dple). Total leucocyte numbers did not differ markedly among the groups. Significant differences were registered when values from control and animals harboring each larval stage of D. hominis were compared; with crescent rank: L1-, L2-, control and L3-infected groups. Leucocyte numbers were significantly higher in the control, 15, 20 or 28 dpi groups than in the 6 dpi animals. Higher counts were observed in control, L2- or L3-infected rats than L1-infected animals. Neutrophils, eosinophils and both large and small lymphocytes were also counted and analyzed. Basophils and monocytes were insufficient in number to permit statistical studies. These results stimulate the continuity of the studies about the host-parasite relationship in the dermatobiosis. FAU - Goncalves, Jomara M AU - Goncalves JM AD - Departamento de Parasitologia, Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil. FAU - Pereira, Monica C T AU - Pereira MC FAU - Evangelista, Luciene G AU - Evangelista LG FAU - Leite, Antonio C R AU - Leite AC LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Brazil TA - Rev Inst Med Trop Sao Paulo JT - Revista do Instituto de Medicina Tropical de Sao Paulo JID - 7507484 SB - IM MH - Animals MH - *Diptera MH - Disease Models, Animal MH - Host-Parasite Interactions/immunology MH - Larva MH - Leukocyte Count MH - *Leukocytes MH - Male MH - Myiasis/*blood/immunology MH - Rats MH - Time Factors EDAT- 2007/11/21 09:00 MHDA- 2008/05/16 09:00 CRDT- 2007/11/21 09:00 PHST- 2006/09/22 00:00 [received] PHST- 2007/05/16 00:00 [accepted] PHST- 2007/11/21 09:00 [pubmed] PHST- 2008/05/16 09:00 [medline] PHST- 2007/11/21 09:00 [entrez] AID - S0036-46652007000500003 [pii] AID - 10.1590/s0036-46652007000500003 [doi] PST - ppublish SO - Rev Inst Med Trop Sao Paulo. 2007 Sep-Oct;49(5):289-92. doi: 10.1590/s0036-46652007000500003.