PMID- 18029333 OWN - NLM STAT- MEDLINE DCOM- 20080123 LR - 20191110 IS - 0741-238X (Print) IS - 0741-238X (Linking) VI - 24 IP - 5 DP - 2007 Sep-Oct TI - Comparison of myocardial performance index versus ratio of isovolumic contraction time/ejection time in left ventricular systolic dysfunction. PG - 1061-7 AB - Myocardial performance index (MPI) has been regarded as an important parameter in the evaluation of ventricular systolic function in congestive heart failure. This study was designed to investigate the relationship between the ratio of isovolumic contraction time/left ventricular ejection time (IVCT/LVET), MPI, and LV systolic function. A total of 43 patients (patient group) with LV ejection fractions (LVEFs) <55% were compared with 43 patients (control group) with LVEF values >or=55%. LVEF was measured in all cases by 2-dimensional echocardiography via the modified Simpson method. Isovolumic relaxation time (IVRT), IVCT, LVET, ratio of IVCT/LVET, and MPI ([IVRT+IVCT]/LVET) were measured via Doppler echocardiography. The mean value for IVCT was found to be significantly higher (P<.001) and concomitant mean LVET value significantly lower (P=.027) in the patient group. Similarly, the mean value of MPI and the ratio of IVCT/LVET were found to be significantly higher (P<.001 for both) in the patient group. The value of the ratio of IVCT/LVET was found to have a significant negative correlation with the value of LVEF (r=-.947; P<.001) and a significant positive correlation with the value of MPI (r=.796; P<.001). The study reported here clearly demonstrates the noninferiority of the ratio of IVCT/LVET to MPI and the possibility of its substitution for MPI in the evaluation of LV systolic function. FAU - Yilmaz, Ahmet AU - Yilmaz A AD - Department of Cardiology, Cumhuriyet University, Sivas, Turkey. FAU - Yalta, Kenan AU - Yalta K FAU - Turgut, Okan Onur AU - Turgut OO FAU - Yilmaz, Mehmet Birhan AU - Yilmaz MB FAU - Ozyol, Ali AU - Ozyol A FAU - Erdem, Alim AU - Erdem A FAU - Tandogan, Izzet AU - Tandogan I LA - eng PT - Journal Article PL - United States TA - Adv Ther JT - Advances in therapy JID - 8611864 MH - Aged MH - Echocardiography MH - Female MH - Humans MH - Male MH - *Myocardial Contraction MH - Sensitivity and Specificity MH - Severity of Illness Index MH - *Stroke Volume MH - Systole MH - Ventricular Dysfunction, Left/*diagnosis/physiopathology EDAT- 2007/11/22 09:00 MHDA- 2008/01/24 09:00 CRDT- 2007/11/22 09:00 PHST- 2007/11/22 09:00 [pubmed] PHST- 2008/01/24 09:00 [medline] PHST- 2007/11/22 09:00 [entrez] AID - 691 [pii] AID - 10.1007/BF02877712 [doi] PST - ppublish SO - Adv Ther. 2007 Sep-Oct;24(5):1061-7. doi: 10.1007/BF02877712.