PMID- 18036399 OWN - NLM STAT- MEDLINE DCOM- 20080122 LR - 20131121 IS - 0165-4608 (Print) IS - 0165-4608 (Linking) VI - 179 IP - 2 DP - 2007 Dec TI - Confirmation of a novel recurrent association: BCR-ABL t(9;22) and t(19;21). PG - 127-31 AB - Association of a t(9;22)(q34;q11), BCR/ABL-positive, with a dic(19;21)(p13;p13) has been described in acute lymphoblastic leukemia in relapse, raising the question of whether this association is recurrent. Described here are two cases, one of myeloproliferative disease and one of acute lymphoblastic leukemia, both presenting a masked t(9;22) and t(19;21). Chromosomal rearrangements were ascertained by fluorescence in situ hybridization (FISH) using locus-specific probes, multicolor FISH, and bacterial artificial chromosome array. These additional observations suggest a nonrandom association. FAU - Struski, Stephanie AU - Struski S AD - Institute of Hematology, Faculty of Medicine, 4 rue Kirschleger, 67000 Strasbourg, France. Stephanie.struski@chru-strasbourg.fr FAU - Helias, Catherine AU - Helias C FAU - Gervais, Carine AU - Gervais C FAU - Leymarie, Vincent AU - Leymarie V FAU - Audhuy, Bruno AU - Audhuy B FAU - Moskovtchenko, Philippe AU - Moskovtchenko P FAU - Lutz, Patrick AU - Lutz P FAU - Gaub, Marie-Pierre AU - Gaub MP FAU - Lessard, Michel AU - Lessard M LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Cancer Genet Cytogenet JT - Cancer genetics and cytogenetics JID - 7909240 RN - EC 2.7.10.2 (Fusion Proteins, bcr-abl) SB - IM MH - Adolescent MH - Aged MH - Burkitt Lymphoma/*genetics MH - *Chromosomes, Human, Pair 19 MH - *Chromosomes, Human, Pair 21 MH - *Chromosomes, Human, Pair 22 MH - *Chromosomes, Human, Pair 9 MH - Female MH - Fusion Proteins, bcr-abl/*metabolism MH - Humans MH - In Situ Hybridization, Fluorescence MH - Male MH - Myeloproliferative Disorders/*genetics MH - *Translocation, Genetic EDAT- 2007/11/27 09:00 MHDA- 2008/01/23 09:00 CRDT- 2007/11/27 09:00 PHST- 2007/08/10 00:00 [received] PHST- 2007/08/14 00:00 [accepted] PHST- 2007/11/27 09:00 [pubmed] PHST- 2008/01/23 09:00 [medline] PHST- 2007/11/27 09:00 [entrez] AID - S0165-4608(07)00496-7 [pii] AID - 10.1016/j.cancergencyto.2007.08.004 [doi] PST - ppublish SO - Cancer Genet Cytogenet. 2007 Dec;179(2):127-31. doi: 10.1016/j.cancergencyto.2007.08.004.