PMID- 18037349
OWN - NLM
STAT- MEDLINE
DCOM- 20081028
LR  - 20220331
IS  - 1529-9430 (Print)
IS  - 1529-9430 (Linking)
VI  - 8
IP  - 5
DP  - 2008 Sep-Oct
TI  - Metastasis of carcinoid to the arch of the axis in a multiple endocrine neoplasia 
      patient: a case report.
PG  - 841-4
AB  - BACKGROUND CONTEXT: Carcinoid tumors eventually metastasize to the spine, and 
      epidural spinal cord compression is a relatively frequent neurologic complication 
      of carcinoid. However, a case of multiple endocrine neoplasia type 1 (MEN1) 
      presenting with spinal cord compression as a result of a metastatic carcinoid 
      tumor has not been reported previously. PURPOSE: To report an extremely rare case 
      of MEN1 presenting with spinal cord compression by metastatic carcinoid tumor. 
      STUDY DESIGN: Case report. METHODS: A 51-year-old man, with a past history of 
      thymoma, insulinoma, and gastric carcinoid presented with neck pain. 
      Neuroradiological examination revealed that a tumor around the arch of the axis 
      compressed the spinal cord with osteoblastic changes. RESULTS: After 
      hemilaminectomy of the axis and removal of the tumor followed by irradiation, the 
      patient returned to his previous job. Histological examination confirmed 
      metastatic carcinoid tumor. CONCLUSIONS: Spinal metastasis of carcinoid tumor 
      occurred in a multiple endocrine neoplasia patient, and it is significant to note 
      that carcinoid metastasis is one of differential diagnoses for osteoblastic 
      lesions.
FAU - Tanabe, Michiharu
AU  - Tanabe M
AD  - Department of Neurosurgery, Gamma-Knife Center, Takashima Hospital, Yonago 
      6830826, Japan. mbbmichi@hotmail.com
FAU - Akatsuka, Keiichi
AU  - Akatsuka K
FAU - Umeda, Seiichi
AU  - Umeda S
FAU - Shomori, Kohei
AU  - Shomori K
FAU - Taniura, Seijiro
AU  - Taniura S
FAU - Okamoto, Hisayo
AU  - Okamoto H
FAU - Kamitani, Hideki
AU  - Kamitani H
FAU - Watanabe, Takashi
AU  - Watanabe T
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20071126
PL  - United States
TA  - Spine J
JT  - The spine journal : official journal of the North American Spine Society
JID - 101130732
SB  - IM
MH  - Adult
MH  - Axis, Cervical Vertebra/*pathology/surgery
MH  - Carcinoid Tumor/*secondary/surgery
MH  - Humans
MH  - Insulinoma/pathology
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*pathology/surgery
MH  - Spinal Neoplasms/*secondary/surgery
MH  - Stomach Neoplasms/*pathology
MH  - Thymoma/pathology
EDAT- 2007/11/27 09:00
MHDA- 2008/10/29 09:00
CRDT- 2007/11/27 09:00
PHST- 2007/01/31 00:00 [received]
PHST- 2007/04/19 00:00 [revised]
PHST- 2007/06/26 00:00 [accepted]
PHST- 2007/11/27 09:00 [pubmed]
PHST- 2008/10/29 09:00 [medline]
PHST- 2007/11/27 09:00 [entrez]
AID - S1529-9430(07)00270-7 [pii]
AID - 10.1016/j.spinee.2007.06.015 [doi]
PST - ppublish
SO  - Spine J. 2008 Sep-Oct;8(5):841-4. doi: 10.1016/j.spinee.2007.06.015. Epub 2007 
      Nov 26.