PMID- 18038168
OWN - NLM
STAT- MEDLINE
DCOM- 20080617
LR  - 20211020
IS  - 0301-0449 (Print)
IS  - 0301-0449 (Linking)
VI  - 38
IP  - 1
DP  - 2008 Jan
TI  - Imaging in unilateral Wilms tumour.
PG  - 18-29
AB  - Wilms tumour is one of the most common malignancies in children, with an 
      excellent prognosis after therapy. There is a very diverse approach to treatment 
      according to geographical location. This variation in therapeutic attitude toward 
      Wilms tumour, particularly between the United States and Europe, has consequences 
      for the choice of imaging modality at diagnosis. In Europe, the International 
      Society of Paediatric Oncology (SIOP) treatment protocol is based on chemotherapy 
      followed by surgery. Imaging (US, CT and MRI), clinical history and examination 
      will help predict whether the findings are consistent with Wilms tumour. 
      Furthermore, in the UK preoperative image-guided biopsy is advised to help 
      identify the small group of patients who, despite typical imaging features of 
      Wilms tumour, have other types of neoplasia that require alternative management. 
      In the United States, the National Wilms Tumor Study (NWTS) advises surgery prior 
      to chemo- and radiotherapy. Hence imaging must provide detailed anatomical 
      information for surgical planning. This article discusses the role of imaging at 
      diagnosis and the relative strengths and weaknesses of the available radiological 
      techniques. We also focus on imaging the lung for metastatic disease and the 
      consequences (to the patient's ultimate outcome) of CT-diagnosed small pulmonary 
      nodules and discuss the radiological diagnosis and consequences of tumour rupture 
      present at diagnosis.
FAU - Brisse, Herve J
AU  - Brisse HJ
AD  - Service de Radiodiagnostic, Institut Curie, 26 Rue d'Ulm, Paris, France. 
      herve.brisse@curie.net
FAU - Smets, Anne M
AU  - Smets AM
FAU - Kaste, Sue C
AU  - Kaste SC
FAU - Owens, Catherine M
AU  - Owens CM
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20071116
PL  - Germany
TA  - Pediatr Radiol
JT  - Pediatric radiology
JID - 0365332
SB  - IM
CIN - Pediatr Radiol. 2008 Jan;38(1):1. PMID: 18026722
CIN - Pediatr Radiol. 2008 Jul;38(7):817-8; author reply 819-20. PMID: 18443777
MH  - Biopsy
MH  - Child
MH  - *Diagnostic Imaging
MH  - Humans
MH  - Kidney Neoplasms/*diagnosis/pathology/therapy
MH  - Lung Neoplasms/secondary
MH  - Neoplasm Metastasis
MH  - Neoplasm Recurrence, Local
MH  - Risk Factors
MH  - Rupture, Spontaneous/diagnosis
MH  - Wilms Tumor/*diagnosis/pathology/therapy
RF  - 45
EDAT- 2007/11/27 09:00
MHDA- 2008/06/18 09:00
CRDT- 2007/11/27 09:00
PHST- 2007/05/22 00:00 [received]
PHST- 2007/10/12 00:00 [accepted]
PHST- 2007/09/24 00:00 [revised]
PHST- 2007/11/27 09:00 [pubmed]
PHST- 2008/06/18 09:00 [medline]
PHST- 2007/11/27 09:00 [entrez]
AID - 10.1007/s00247-007-0677-9 [doi]
PST - ppublish
SO  - Pediatr Radiol. 2008 Jan;38(1):18-29. doi: 10.1007/s00247-007-0677-9. Epub 2007 
      Nov 16.