PMID- 18039207
OWN - NLM
STAT- MEDLINE
DCOM- 20080220
LR  - 20071127
IS  - 0886-0440 (Print)
IS  - 0886-0440 (Linking)
VI  - 22
IP  - 6
DP  - 2007 Nov-Dec
TI  - Mild or moderate ischemic mitral regurgitation in patients undergoing off-pump 
      coronary artery bypass grafting.
PG  - 480-5
AB  - BACKGROUND: There has been a debate, whether mild or moderate ischemic mitral 
      regurgitation (IMR) should be repaired at the time of coronary bypass surgery. We 
      assessed the early and midterm outcomes of patients with mild or moderate IMR who 
      underwent isolated off-pump coronary artery bypass grafting (OPCAB). METHODS: We 
      retrospectively reviewed records of 602 patients who underwent OPCAB between 
      April 2001 and July 2004. Of those, 96 patients had mild or moderate MR (IMR 
      group), and 506 had none or trivial MR (no IMR group). Preoperative and 
      postoperative characteristics were compared between the groups. Furthermore, 
      fates of grade of MR and functional status were investigated in patients with 
      IMR. RESULTS: The preoperative mean New York Heart Association (NYHA) classes 
      were 2.7 +/- 1.0 and 2.4 +/- 0.9 in the IMR and no IMR groups, respectively (p < 
      0.01). Operative mortality was similar between groups (1.0% in the IMR group and 
      0.4% in no IMR group, p = 0.41). The cumulative survival rate for the IMR group 
      was 93.7% at 1 year and 90.1% at 4 years. The mean NYHA class was 1.1 +/- 0.4 (p 
      < 0.0001) at 28.8 +/- 11.4 months after operation for the IMR group. The mean 
      grade of mitral regurgitation diminished (from 2.2 +/- 0.4 to 1.1 +/- 0.6, p < 
      0.0001) soon after operation in patients with IMR, and remained so (1.1 +/- 0.8, 
      p < 0.0001) during the follow-up period. CONCLUSIONS: Mild or moderate IMR could 
      be improved with isolated OPCAB. The early and midterm functional outcomes of 
      these patients were favorable.
FAU - Fukui, Toshihiro
AU  - Fukui T
AD  - Department of Cardiovascular Surgery, Osaka City University Graduate School of 
      Medicine, Osaka, Japan. tm-fukui@gem.hi-ho.ne.jp
FAU - Takanashi, Shuichiro
AU  - Takanashi S
FAU - Tabata, Minoru
AU  - Tabata M
FAU - Hosoda, Yasuyuki
AU  - Hosoda Y
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Aged
MH  - Coronary Artery Bypass/*adverse effects
MH  - *Coronary Artery Bypass, Off-Pump
MH  - Female
MH  - Humans
MH  - Male
MH  - Mitral Valve Insufficiency/*etiology/mortality
MH  - Myocardial Ischemia/*etiology/mortality
MH  - Postoperative Complications
MH  - Postoperative Period
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - *Treatment Outcome
EDAT- 2007/11/28 09:00
MHDA- 2008/02/21 09:00
CRDT- 2007/11/28 09:00
PHST- 2007/11/28 09:00 [pubmed]
PHST- 2008/02/21 09:00 [medline]
PHST- 2007/11/28 09:00 [entrez]
AID - JCS464 [pii]
AID - 10.1111/j.1540-8191.2007.00464.x [doi]
PST - ppublish
SO  - J Card Surg. 2007 Nov-Dec;22(6):480-5. doi: 10.1111/j.1540-8191.2007.00464.x.