PMID- 18042414 OWN - NLM STAT- MEDLINE DCOM- 20080410 LR - 20211027 IS - 1090-7807 (Print) IS - 1096-0856 (Electronic) IS - 1090-7807 (Linking) VI - 190 IP - 2 DP - 2008 Feb TI - Evaluation of sub-microsecond recovery resonators for in vivo electron paramagnetic resonance imaging. PG - 248-54 AB - Time-domain (TD) electron paramagnetic resonance (EPR) imaging at 300MHz for in vivo applications requires resonators with recovery times less than 1 micros after pulsed excitation to reliably capture the rapidly decaying free induction decay (FID). In this study, we tested the suitability of the Litz foil coil resonator (LCR), commonly used in MRI, for in vivo EPR/EPRI applications in the TD mode and compared with parallel coil resonator (PCR). In TD mode, the sensitivity of LCR was lower than that of the PCR. However, in continuous wave (CW) mode, the LCR showed better sensitivity. The RF homogeneity was similar in both the resonators. The axis of the RF magnetic field is transverse to the cylindrical axis of the LCR, making the resonator and the magnet co-axial. Therefore, the loading of animals, and placing of the anesthesia nose cone and temperature monitors was more convenient in the LCR compared to the PCR whose axis is perpendicular to the magnet axis. FAU - Hyodo, F AU - Hyodo F AD - Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1002, USA. FAU - Subramanian, S AU - Subramanian S FAU - Devasahayam, N AU - Devasahayam N FAU - Murugesan, R AU - Murugesan R FAU - Matsumoto, K AU - Matsumoto K FAU - Mitchell, J B AU - Mitchell JB FAU - Krishna, M C AU - Krishna MC LA - eng GR - Z01 BC010476-04/ImNIH/Intramural NIH HHS/United States PT - Comparative Study PT - Journal Article PT - Research Support, N.I.H., Intramural PT - Research Support, Non-U.S. Gov't DEP - 20071107 PL - United States TA - J Magn Reson JT - Journal of magnetic resonance (San Diego, Calif. : 1997) JID - 9707935 RN - 0 (Spin Labels) SB - IM MH - Animals MH - Electron Spin Resonance Spectroscopy/*instrumentation MH - Female MH - Image Processing, Computer-Assisted/instrumentation MH - Mice MH - Mice, Inbred C3H MH - Phantoms, Imaging MH - Sensitivity and Specificity MH - Spin Labels MH - Tail/*blood supply MH - Technology Assessment, Biomedical PMC - PMC2258207 MID - NIHMS39336 EDAT- 2007/11/29 09:00 MHDA- 2008/04/11 09:00 PMCR- 2009/02/01 CRDT- 2007/11/29 09:00 PHST- 2007/06/14 00:00 [received] PHST- 2007/10/16 00:00 [revised] PHST- 2007/11/02 00:00 [accepted] PHST- 2007/11/29 09:00 [pubmed] PHST- 2008/04/11 09:00 [medline] PHST- 2007/11/29 09:00 [entrez] PHST- 2009/02/01 00:00 [pmc-release] AID - S1090-7807(07)00341-2 [pii] AID - 10.1016/j.jmr.2007.11.004 [doi] PST - ppublish SO - J Magn Reson. 2008 Feb;190(2):248-54. doi: 10.1016/j.jmr.2007.11.004. Epub 2007 Nov 7.