PMID- 18046055 OWN - NLM STAT- MEDLINE DCOM- 20071226 LR - 20191110 IS - 1526-484X (Print) IS - 1526-484X (Linking) VI - 17 IP - 5 DP - 2007 Oct TI - The effects of nutritional supplementation throughout an endurance run on leucine kinetics during recovery. PG - 456-67 AB - This study determined the effect of nutritional supplementation throughout endurance exercise on whole-body leucine kinetics (leucine rate of appearance [Ra], oxidation [Ox], and nonoxidative leucine disposal [NOLD]) during recovery. Five trained men underwent a 2-h run at 65% VO(2max), during which a carbohydrate (CHO), mixed protein-carbohydrate (milk), or placebo (PLA) drink was consumed. Leucine kinetics were assessed during recovery using a primed, continuous infusion of 1-13C leucine. Leucine Ra and NOLD were lower for milk than for PLA. Ox was higher after milk-supplemented exercise than after CHO or PLA. Although consuming milk during the run affected whole-body leucine kinetics, the benefits of such a practice for athletes remain unclear. Additional studies are needed to determine whether protein supplementation during exercise can optimize protein utilization during recovery. FAU - Miller, Sharon L AU - Miller SL AD - Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA. FAU - Gaine, P Courtney AU - Gaine PC FAU - Maresh, Carl M AU - Maresh CM FAU - Armstrong, Lawrence E AU - Armstrong LE FAU - Ebbeling, Cara B AU - Ebbeling CB FAU - Lamont, Linda S AU - Lamont LS FAU - Rodriguez, Nancy R AU - Rodriguez NR LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't PL - United States TA - Int J Sport Nutr Exerc Metab JT - International journal of sport nutrition and exercise metabolism JID - 100939812 RN - 0 (Carbon Isotopes) RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Proteins) RN - GMW67QNF9C (Leucine) SB - IM MH - Adolescent MH - Adult MH - Animals MH - Carbon Isotopes MH - Cross-Over Studies MH - Dietary Carbohydrates/metabolism/*pharmacology MH - Dietary Proteins/metabolism/*pharmacology MH - *Dietary Supplements MH - Energy Metabolism MH - Humans MH - Leucine/*pharmacokinetics MH - Male MH - Milk MH - Oxygen Consumption MH - Physical Endurance/*physiology EDAT- 2007/11/30 09:00 MHDA- 2007/12/27 09:00 CRDT- 2007/11/30 09:00 PHST- 2007/11/30 09:00 [pubmed] PHST- 2007/12/27 09:00 [medline] PHST- 2007/11/30 09:00 [entrez] AID - 10.1123/ijsnem.17.5.456 [doi] PST - ppublish SO - Int J Sport Nutr Exerc Metab. 2007 Oct;17(5):456-67. doi: 10.1123/ijsnem.17.5.456.