PMID- 18046057
OWN - NLM
STAT- MEDLINE
DCOM- 20071226
LR  - 20191110
IS  - 1526-484X (Print)
IS  - 1526-484X (Linking)
VI  - 17
IP  - 5
DP  - 2007 Oct
TI  - Influence of carbohydrate, intense exercise, and rest intervals on hormonal and 
      oxidative changes.
PG  - 478-90
AB  - This study compared effects of carbohydrate (CHO) and rest on oxidative stress 
      during exercise. Cyclists (N = 12) completed 4 randomized trials at 64% Wattsmax 
      under 2 conditions (continuous cycling for 2 h [C] and cycling with 3-min rest 
      every 10 min for 2.6 h [R]). Subjects cycled under each condition while receiving 
      6% CHO and placebo (PLA). CHO and PLA were given preexercise (12 mL/kg) and 
      during exercise (4 mL x kg(-1) x 15 min(-1)). Blood was collected preexercise, 
      postexercise, and 1 h postexercise and assayed for F2-isoprostanes, 
      hydroperoxides (LH), nitrite, antioxidant capacity, glucose, insulin, cortisol, 
      and epinephrine. F2-isoprostanes and LH were lower in CHO. Glucose, cortisol, and 
      epinephrine exhibited significant effects, with postexercise levels of glucose 
      higher and cortisol and epinephrine lower in CHO during the R condition. This 
      pattern was identical in the C condition (21). Oxidative stress during cycling 
      was unaffected by use of short rest intervals but was diminished by CHO.
FAU - McAnulty, Steven R
AU  - McAnulty SR
AD  - Dept. of Health, Leisure, and Exercise Science, Appalachian State University, 
      Boone, NC 28608, USA.
FAU - McAnulty, Lisa S
AU  - McAnulty LS
FAU - Morrow, Jason D
AU  - Morrow JD
FAU - Nieman, David C
AU  - Nieman DC
FAU - Owens, John T
AU  - Owens JT
FAU - Carper, Cristin M
AU  - Carper CM
LA  - eng
GR  - CA-77839/CA/NCI NIH HHS/United States
GR  - DK-48831/DK/NIDDK NIH HHS/United States
GR  - GM-15431/GM/NIGMS NIH HHS/United States
GR  - RR00095/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Int J Sport Nutr Exerc Metab
JT  - International journal of sport nutrition and exercise metabolism
JID - 100939812
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (F2-Isoprostanes)
RN  - 0 (Insulin)
RN  - 0 (Nitrites)
RN  - BBX060AN9V (Hydrogen Peroxide)
RN  - WI4X0X7BPJ (Hydrocortisone)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Adult
MH  - Bicycling
MH  - Cross-Over Studies
MH  - Dietary Carbohydrates/*pharmacology
MH  - Epinephrine/blood
MH  - F2-Isoprostanes/blood
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Hydrogen Peroxide/blood
MH  - Insulin/blood
MH  - Male
MH  - Nitrites/blood
MH  - Oxidative Stress/*drug effects
MH  - Physical Education and Training/methods
MH  - Physical Endurance/drug effects/*physiology
MH  - Physical Exertion/drug effects/physiology
EDAT- 2007/11/30 09:00
MHDA- 2007/12/27 09:00
CRDT- 2007/11/30 09:00
PHST- 2007/11/30 09:00 [pubmed]
PHST- 2007/12/27 09:00 [medline]
PHST- 2007/11/30 09:00 [entrez]
AID - 10.1123/ijsnem.17.5.478 [doi]
PST - ppublish
SO  - Int J Sport Nutr Exerc Metab. 2007 Oct;17(5):478-90. doi: 
      10.1123/ijsnem.17.5.478.