PMID- 18048614
OWN - NLM
STAT- MEDLINE
DCOM- 20080402
LR  - 20211020
IS  - 1468-3318 (Electronic)
IS  - 0964-4563 (Print)
IS  - 0964-4563 (Linking)
VI  - 16
IP  - 6
DP  - 2007 Dec
TI  - Use of nicotine replacement therapy to reduce or delay smoking but not to quit: 
      prevalence and association with subsequent cessation efforts.
PG  - 384-9
AB  - OBJECTIVE: To assess the prevalence of nicotine replacement therapy (NRT) use for 
      purposes other than quitting smoking and examine the relation of this 
      non-standard NRT use (NSNRT) with subsequent smoking cessation efforts. DESIGN: A 
      population based cohort study of adult smokers who were interviewed by telephone 
      at baseline (2001-2) and at two year follow-up. The association between NSNRT use 
      to cut down on smoking or to delay smoking before baseline and cessation attempts 
      and smoking outcomes at two year follow-up was assessed using logistic regression 
      to adjust for multiple potential confounding factors. SETTING: Massachusetts, 
      USA. SUBJECTS: 1712 adult smokers in Massachusetts who were selected using a 
      random digit dial telephone survey. MAIN OUTCOME MEASURES: Quit attempt in 12 
      months before follow-up, NRT use at quit attempt in 12 months before follow-up, 
      smoking cessation by follow-up, or 50% reduction in cigarettes smoked per day 
      between baseline and follow-up. RESULTS: 18.7% of respondents reported ever 
      having used NSNRT. In a multiple logistic regression analysis, there was no 
      statistically significant association between past NSNRT use and quit attempts 
      (OR(cut down) = 0.89, 95% CI 0.59 to 1.33; OR(delay) = 1.29, 95% CI 0.73 to 
      2.29), smoking cessation (OR(cut down) = 0.74, 95% CI 0.43 to 1.24; OR(delay) = 
      1.22, 95% CI 0.60 to 2.50) or 50% reduction in cigarettes smoked per day (OR(cut 
      down) = 0.93, 95% CI 0.62 to 1.38; OR(delay) = 0.80, 95% CI 0.43 to 1.49) at 
      follow-up. Past use of NRT to cut down on cigarettes was associated with use of 
      NRT at a follow-up quit attempt (OR(cut down) = 2.28, 95% CI 1.50 to 3.47) but 
      past use of NRT to delay smoking was not (OR(delay) = 1.25, 95% CI 0.67 to 2.34). 
      CONCLUSIONS: Use of NRT for reasons other than quitting smoking may be more 
      common than was previously estimated. This population based survey finds no 
      strong evidence that NRT use for purposes other than quitting smoking is either 
      harmful or helpful.
FAU - Levy, Douglas E
AU  - Levy DE
AD  - Institute for Health Policy, Massachusetts General Hospital, 50 Staniford Street, 
      9th floor, Boston, MA 02114, USA. douglas_levy@hms2.harvard.edu
FAU - Thorndike, Anne N
AU  - Thorndike AN
FAU - Biener, Lois
AU  - Biener L
FAU - Rigotti, Nancy A
AU  - Rigotti NA
LA  - eng
GR  - R01 CA086257/CA/NCI NIH HHS/United States
GR  - R01 CA086257-07/CA/NCI NIH HHS/United States
GR  - K24-HL04440/HL/NHLBI NIH HHS/United States
GR  - R01-CA86257/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - England
TA  - Tob Control
JT  - Tobacco control
JID - 9209612
RN  - 0 (Nicotinic Agonists)
RN  - 6M3C89ZY6R (Nicotine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Female
MH  - Follow-Up Studies
MH  - Health Behavior
MH  - Humans
MH  - Male
MH  - Massachusetts/epidemiology
MH  - Middle Aged
MH  - Nicotine/*administration & dosage
MH  - Nicotinic Agonists/*administration & dosage
MH  - Prevalence
MH  - Prospective Studies
MH  - Smoking/*epidemiology
MH  - Smoking Cessation/*methods
MH  - Smoking Prevention
PMC - PMC2807189
COIS- Competing interests: NAR has received research grants from Pfizer, 
      Sanofi-Aventis, Nabi Biopharmaceuticals, and Glaxo Smith Kline. She has consulted 
      for Pfizer and Sanofi-Aventis. The other authors report no competing interests.
EDAT- 2007/12/01 09:00
MHDA- 2008/04/03 09:00
PMCR- 2010/12/01
CRDT- 2007/12/01 09:00
PHST- 2007/12/01 09:00 [pubmed]
PHST- 2008/04/03 09:00 [medline]
PHST- 2007/12/01 09:00 [entrez]
PHST- 2010/12/01 00:00 [pmc-release]
AID - 16/6/384 [pii]
AID - tc21485 [pii]
AID - 10.1136/tc.2007.021485 [doi]
PST - ppublish
SO  - Tob Control. 2007 Dec;16(6):384-9. doi: 10.1136/tc.2007.021485.