PMID- 18054079 OWN - NLM STAT- MEDLINE DCOM- 20081021 LR - 20080519 IS - 0160-4120 (Print) IS - 0160-4120 (Linking) VI - 34 IP - 4 DP - 2008 May TI - Monitoring concentrations of persistent organic pollutants in the general population: the international experience. PG - 546-61 AB - Assessing the adverse effects on human health of persistent organic pollutants (POPs) and the impact of policies aiming to reduce human exposure to POPs warrants monitoring body concentrations of POPs in representative samples of subjects. While numerous ad hoc studies are being conducted to understand POPs effects, only a few countries are conducting nationwide surveillance programs of human concentrations of POPs, and even less countries do so in representative samples of the general population. We tried to identify all studies worldwide that analyzed the distribution of concentrations of POPs in a representative sample of the general population, and we synthesized the studies' main characteristics, as design, population, and chemicals analyzed. The most comprehensive studies are the National Reports on Human Exposure to Environmental Chemicals (USA), the German Environmental Survey, and the Arctic Monitoring and Assessment Programme. Population-wide studies exist as well in New Zealand, Australia, Japan, Flanders (Belgium) and the Canary Islands (Spain). Most such studies are linked with health surveys, which is a highly-relevant additional strength. Only the German and Flemish studies analyzed POPs by educational level, while studies in the USA offer results by ethnic group. The full distribution of POPs concentrations is unknown in many countries. Knowledge gaps include also the interplay of age, gender, period and cohort effects on the prevalence of exposures observed by cross-sectional surveys. Local and global efforts to minimize POPs contamination, like the Stockholm convention, warrant nationwide monitoring of concentrations of POPs in representative samples of the general population. Results of this review show how such studies may be developed and used. FAU - Porta, Miquel AU - Porta M AD - Institut Municipal d'Investigacio Medica, Barcelona, Spain. mporta@imim.es FAU - Puigdomenech, Elisa AU - Puigdomenech E FAU - Ballester, Ferran AU - Ballester F FAU - Selva, Javier AU - Selva J FAU - Ribas-Fito, Nuria AU - Ribas-Fito N FAU - Llop, Sabrina AU - Llop S FAU - Lopez, Tomas AU - Lopez T LA - eng PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20071203 PL - Netherlands TA - Environ Int JT - Environment international JID - 7807270 RN - 0 (Environmental Pollutants) RN - 0 (Organic Chemicals) SB - IM MH - Environmental Monitoring/*methods MH - Environmental Pollutants/*analysis MH - *Human Body MH - Humans MH - Internationality MH - Organic Chemicals/*analysis RF - 91 EDAT- 2007/12/07 09:00 MHDA- 2008/10/22 09:00 CRDT- 2007/12/07 09:00 PHST- 2007/04/23 00:00 [received] PHST- 2007/10/05 00:00 [revised] PHST- 2007/10/15 00:00 [accepted] PHST- 2007/12/07 09:00 [pubmed] PHST- 2008/10/22 09:00 [medline] PHST- 2007/12/07 09:00 [entrez] AID - S0160-4120(07)00197-3 [pii] AID - 10.1016/j.envint.2007.10.004 [doi] PST - ppublish SO - Environ Int. 2008 May;34(4):546-61. doi: 10.1016/j.envint.2007.10.004. Epub 2007 Dec 3.