PMID- 18054288
OWN - NLM
STAT- MEDLINE
DCOM- 20080318
LR  - 20080114
IS  - 1525-5050 (Print)
IS  - 1525-5050 (Linking)
VI  - 12
IP  - 2
DP  - 2008 Feb
TI  - Ictal neuropsychological findings in focal nonconvulsive status epilepticus.
PG  - 269-75
AB  - OBJECTIVE: This study was intended to describe the neuropsychological 
      phenomenology of focal nonconvulsive status epilepticus (NCSE). METHODS: Ictal, 
      postictal, and interictal neuropsychological testing (NPT) was performed on six 
      patients who developed NCSE during video/electroencephalographic monitoring in 
      the context of presurgical evaluation. RESULTS: Neuropsychological impairments 
      were marked in four of six and discrete in two of six patients. The majority of 
      patients had selective rather than global neuropsychological deficits. The most 
      important deficits involved consciousness, speech, praxis, cognitive functions, 
      and affect. Impairment of consciousness was characterized by reduced vigilance, 
      reactivity, and orientation. Some patients exhibited combined deficits of several 
      higher cognitive functions (apraxia, acalculia, alexia, and aphasia with or 
      without additional memory disturbance). Several patients had relatively subtle 
      expressive or receptive aphasia. More severe language deficits were associated 
      with reduced vigilance. Speech deficits may have caused poor performance in other 
      areas evaluated with NPT. CONCLUSION: NPT demonstrated that focal NCSE can be 
      associated with pleomorphic but often discrete neuropsychological deficits.
FAU - Profitlich, Thomas
AU  - Profitlich T
AD  - Department of Epileptology, University of Bonn, Bonn, Germany.
FAU - Hoppe, Christian
AU  - Hoppe C
FAU - Reuber, Markus
AU  - Reuber M
FAU - Helmstaedter, Christoph
AU  - Helmstaedter C
FAU - Bauer, Jurgen
AU  - Bauer J
LA  - eng
PT  - Journal Article
DEP - 20071128
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
SB  - IM
MH  - Adult
MH  - Cerebral Cortex/*physiopathology
MH  - Cognition Disorders/complications/*diagnosis/physiopathology
MH  - Consciousness Disorders/complications/diagnosis/physiopathology
MH  - Electroencephalography
MH  - Female
MH  - Humans
MH  - Language Disorders/complications/*diagnosis/physiopathology
MH  - Male
MH  - Memory Disorders/complications/*diagnosis/physiopathology
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Retrospective Studies
MH  - Seizures/physiopathology
MH  - Status Epilepticus/complications/*diagnosis/physiopathology
EDAT- 2007/12/07 09:00
MHDA- 2008/03/19 09:00
CRDT- 2007/12/07 09:00
PHST- 2006/07/10 00:00 [received]
PHST- 2007/10/22 00:00 [revised]
PHST- 2007/10/22 00:00 [accepted]
PHST- 2007/12/07 09:00 [pubmed]
PHST- 2008/03/19 09:00 [medline]
PHST- 2007/12/07 09:00 [entrez]
AID - S1525-5050(07)00363-0 [pii]
AID - 10.1016/j.yebeh.2007.10.011 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2008 Feb;12(2):269-75. doi: 10.1016/j.yebeh.2007.10.011. Epub 
      2007 Nov 28.