PMID- 18058249
OWN - NLM
STAT- MEDLINE
DCOM- 20080415
LR  - 20211203
IS  - 0967-3849 (Print)
IS  - 0967-3849 (Linking)
VI  - 15
IP  - 8
DP  - 2007
TI  - Chromosomal evolution in tenrecs (Microgale and Oryzorictes, Tenrecidae) from the 
      Central Highlands of Madagascar.
PG  - 1075-91
AB  - Tenrecs (Tenrecidae) are a widely diversified assemblage of small eutherian 
      mammals that occur in Madagascar and Western and Central Africa. With the 
      exception of a few early karyotypic descriptions based on conventional staining, 
      nothing is known about the chromosomal evolution of this family. We present a 
      detailed analysis of G-banded and molecularly defined chromosomes based on 
      fluorescence in situ hybridization (FISH) that allows a comprehensive comparison 
      between the karyotypes of 11 species of two closely related Malagasy genera, 
      Microgale (10 species) and Oryzorictes (one species), of the subfamily 
      Oryzorictinae. The karyotypes of Microgale taiva and M. parvula (2n = 32) were 
      found to be identical to that of O. hova (2n = 32) most likely reflecting the 
      ancestral karyotypes of both genera, as well as that of the Oryzorictinae. 
      Parsimony analysis of chromosomal rearrangements that could have arisen following 
      Whole Arm Reciprocal Translocations (WARTs) showed, however, that these are more 
      likely to be the result of Robertsonian translocations. A single most 
      parsimonious tree was obtained that provides strong support for three species 
      associations within Microgale, all of which are consistent with previous 
      molecular and morphological investigations. By expanding on a recently published 
      molecular clock for the Tenrecidae we were able to place our findings in a 
      temporal framework that shows strong chromosomal rate heterogeneity within the 
      Oryzorictinae. We use these data to critically examine the possible role of 
      chromosomal rearrangements in speciation within Microgale.
FAU - Gilbert, C
AU  - Gilbert C
AD  - Evolutionary Genomics Group, Department of Botany and Zoology, University of 
      Stellenbosch, Stellenbosch, South Africa.
FAU - Goodman, S M
AU  - Goodman SM
FAU - Soarimalala, V
AU  - Soarimalala V
FAU - Olson, L E
AU  - Olson LE
FAU - O'Brien, P C M
AU  - O'Brien PC
FAU - Elder, F F B
AU  - Elder FF
FAU - Yang, F
AU  - Yang F
FAU - Ferguson-Smith, M A
AU  - Ferguson-Smith MA
FAU - Robinson, T J
AU  - Robinson TJ
LA  - eng
GR  - Wellcome Trust/United Kingdom
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071106
PL  - Netherlands
TA  - Chromosome Res
JT  - Chromosome research : an international journal on the molecular, supramolecular 
      and evolutionary aspects of chromosome biology
JID - 9313452
SB  - IM
MH  - Animals
MH  - Chromosome Banding
MH  - Chromosome Painting
MH  - Chromosomes, Mammalian/*genetics
MH  - Eulipotyphla/*classification/*genetics
MH  - In Situ Hybridization, Fluorescence
MH  - Karyotyping
MH  - Madagascar
MH  - Translocation, Genetic
EDAT- 2007/12/07 09:00
MHDA- 2008/04/16 09:00
CRDT- 2007/12/07 09:00
PHST- 2007/08/13 00:00 [received]
PHST- 2007/10/02 00:00 [accepted]
PHST- 2007/10/02 00:00 [revised]
PHST- 2007/12/07 09:00 [pubmed]
PHST- 2008/04/16 09:00 [medline]
PHST- 2007/12/07 09:00 [entrez]
AID - 10.1007/s10577-007-1182-6 [doi]
PST - ppublish
SO  - Chromosome Res. 2007;15(8):1075-91. doi: 10.1007/s10577-007-1182-6. Epub 2007 Nov 
      6.