PMID- 18060095
OWN - NLM
STAT- MEDLINE
DCOM- 20080304
LR  - 20211020
IS  - 1198-2241 (Print)
IS  - 1916-7245 (Electronic)
IS  - 1198-2241 (Linking)
VI  - 14
IP  - 8
DP  - 2007 Nov-Dec
TI  - Two sisters with idiopathic pulmonary hemosiderosis.
PG  - 490-3
AB  - Idiopathic pulmonary hemosiderosis (IPH) is a rare cause of diffuse alveolar 
      hemorrhage with unknown etiology. In the present report, the presentations of two 
      sisters are described: one sister had IPH, eosinophilia and a high serum 
      immunoglobulin E (IgE) level; and the other had IPH, pneumothorax, eosinophilia 
      and a high serum IgE level. Both cases had quite unusual presentations. The first 
      patient was 23 years of age, and had suffered from dry cough and progressive 
      dyspnea for four years. Her hemoglobin level was 60 g/L, total serum IgE level 
      was 900 U/mL and eosinophilia was 9%. Her chest radiography revealed diffuse 
      infiltration. She died due to respiratory failure. The second patient was 18 
      years of age. She had also suffered from dry cough and gradually increasing 
      dyspnea for two years. She had partial pneumothorax in the right lung and diffuse 
      infiltration in other pulmonary fields on chest radiography. Her hemoglobin level 
      was 99 g/L, total serum IgE level was 1200 U/mL and eosinophilia was 8%. IPH was 
      diagnosed by open lung biopsy. All these findings suggested that familial or 
      allergic factors, as well as immunological factors, might have contributed to the 
      etiology of IPH.
FAU - Gencer, Mehmet
AU  - Gencer M
AD  - Department of Chest Disease, Faculty of Medicine, Harran University, Sanliurfa, 
      Turkey. drmehmetgencer@yahoo.com
FAU - Ceylan, Erkan
AU  - Ceylan E
FAU - Bitiren, Muharrem
AU  - Bitiren M
FAU - Koc, Ahmet
AU  - Koc A
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Egypt
TA  - Can Respir J
JT  - Canadian respiratory journal
JID - 9433332
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cough/etiology
MH  - Dyspnea/etiology
MH  - Eosinophilia
MH  - Fatal Outcome
MH  - Female
MH  - Hemosiderosis/*complications
MH  - Humans
MH  - Lung Diseases/*pathology
MH  - Pneumothorax/diagnostic imaging/*etiology
MH  - Radiography
MH  - Siblings
PMC - PMC2677775
EDAT- 2007/12/07 09:00
MHDA- 2008/03/05 09:00
PMCR- 2008/11/01
CRDT- 2007/12/07 09:00
PHST- 2007/12/07 09:00 [pubmed]
PHST- 2008/03/05 09:00 [medline]
PHST- 2007/12/07 09:00 [entrez]
PHST- 2008/11/01 00:00 [pmc-release]
AID - crj14490 [pii]
AID - 10.1155/2007/150926 [doi]
PST - ppublish
SO  - Can Respir J. 2007 Nov-Dec;14(8):490-3. doi: 10.1155/2007/150926.