PMID- 18060610 OWN - NLM STAT- MEDLINE DCOM- 20080212 LR - 20091103 IS - 0340-9937 (Print) IS - 0340-9937 (Linking) VI - 32 IP - 8 DP - 2007 Dec TI - [Treatment of acute ST Elevation myocardial infarction in a regional network ("Drip & Ship Network Rostock")]. PG - 635-40 AB - Management of acute ST elevation myocardial infarction (STEMI) demands rapid and complete reperfusion of the infarct-related artery (IRA). With postinfarction prognosis depending on time delay from onset of symptoms to complete reperfusion (TIMI 3 flow) of the IRA, primary percutaneous coronary intervention (PPCI) performed by an experienced team has been shown to be superior to thrombolytic therapy with lower mortality, less frequent occurrence of nonfatal reinfarction and stroke, and thus represents the preferred treatment strategy according to the national and international guidelines. For regional implementation of PPCI, particularly in rural areas, information and transfer logistics within networks of care and direct transport of an infarction patient to a PCI hospital rather than to the closest hospital are a challenge. With successful implementation of network logistics and standardized therapeutic pathways, current guidelines and requested timelines versus thrombolysis could be met. The implemented logistics comprised 24 h/7 days stand-by services of an experienced PCI team, direct telephone hotline contact between rescue service/emergency physician and interventional cardiologist on call, and direct open access to a catheterization laboratory at any time. Within the Drip&Ship network Rostock, to date (July 2007) 1,022 consecutive patients with PCI for STEMI were documented and analyzed over 5 years; of these, 490 patients were transferred from a community hospital to the PCI center and 532 patients were admitted directly to the interventional center. In 95.1% of all transferred and in 94.8% of all directly admitted patients, PCI was successfully accomplished upon arrival. A normalized flow to the IRA after PCI was documented in 96% of both groups, no patient was subjected to thrombolytic therapy. At 12-month follow-up, there were no differences between both groups with respect to infarct size and mortality. Moreover, there was no evidence of differences in left ventricular ejection fraction between groups. Thus, transportation of STEMI patients within an established PCI network did not result in any prognostic disadvantage. Efficient network logistics with transportation for PPCI in acute STEMI ensure both safety and outcome profiles similar to patients treated by PCI in metropolitan areas. FAU - Schneider, Henrik AU - Schneider H FAU - Ince, Huseyin AU - Ince H FAU - Rehders, Tim AU - Rehders T FAU - Korber, Thomas AU - Korber T FAU - Weber, Frank AU - Weber F FAU - Kische, Stephan AU - Kische S FAU - Chatterjee, Tuchaar AU - Chatterjee T FAU - Nienaber, Christoph A AU - Nienaber CA CN - Drip&Ship-Netzwerk (District of Rostock Infarct Project & Shipping Patients) LA - ger PT - English Abstract PT - Journal Article PT - Review TT - Behandlung des akuten ST-Hebungsinfarkts in Netzwerkstrukturen: "Drip&Ship -- das Rostocker Infarktmodell". PL - Germany TA - Herz JT - Herz JID - 7801231 SB - IM MH - *Atherectomy MH - Cardiology/*organization & administration MH - Community Networks/*organization & administration MH - Critical Pathways/organization & administration MH - *Decision Support Systems, Clinical MH - Delivery of Health Care/organization & administration MH - Delivery of Health Care, Integrated/organization & administration MH - Germany MH - Humans MH - Models, Organizational MH - Myocardial Infarction/*therapy MH - Regional Health Planning/*organization & administration MH - *Thrombolytic Therapy RF - 19 EDAT- 2007/12/07 09:00 MHDA- 2008/02/13 09:00 CRDT- 2007/12/07 09:00 PHST- 2007/12/07 09:00 [pubmed] PHST- 2008/02/13 09:00 [medline] PHST- 2007/12/07 09:00 [entrez] AID - 10.1007/s00059-007-3061-5 [doi] PST - ppublish SO - Herz. 2007 Dec;32(8):635-40. doi: 10.1007/s00059-007-3061-5.