PMID- 18060768 OWN - NLM STAT- MEDLINE DCOM- 20080925 LR - 20080418 IS - 0960-7404 (Print) IS - 0960-7404 (Linking) VI - 17 IP - 2 DP - 2008 Aug TI - Radiofrequency-assisted liver resection. PG - 81-6 AB - BACKGROUND: Surgical resection remains the treatment of choice for primary, secondary liver cancer and a number of benign liver lesions. Complications are mainly related to blood loss. Radiofrequency-assisted liver resection (RF-LR) has been proposed in order to achieve minimal blood loss during parenchymal transection. PATIENTS AND METHODS: Between May 2005 and April 2007, 46 consecutive patients with various hepatic lesions underwent RF-LR using Radionics, Cool-Tip System. There were 28 men and 18 women with median age 65 years (range 54-76 years). Twelve major and 34 minor hepatectomies were performed for various diseases: hepatocellular carcinoma (n=19), metastatic carcinoma (n=23), focal nodal hyperplasia (n=2) and intrahepatic cholangiocarcinoma (ICC) (n=2). Hepatic inflow occlusion was not used. RESULTS: No perioperative death was documented. Median blood loss was 100ml (range 30-300cm(3)). Blood transfusion was required postoperatively in one patient. Median transection time was 35min (15-60min). Three patients developed biliary fistulas, four patients pleural effusions, one patient hyperbilirubinemia, two pneumonia and four wound infection. The median postoperative hospital stay was 6 days (range 4-10 days). In a median 12 month follow-up (range 3-24 months), four patients with colorectal metastases (CRM) and one patient with ICC developed recurrence. CONCLUSIONS: Cool-Tip RF device provides a unique, simple and safe method of bloodless liver resections and is indicated in cirrhotic patients with challenging hepatectomies (segment VIII, central resections). FAU - Delis, Spiros G AU - Delis SG AD - First Surgical Department, Agia Olga Hospital, 142 33 Athens, Greece. sgdelis55@yahoo.gr FAU - Bakoyiannis, Andreas AU - Bakoyiannis A FAU - Tassopoulos, Nikos AU - Tassopoulos N FAU - Athanasiou, Kostas AU - Athanasiou K FAU - Madariaga, Juan AU - Madariaga J FAU - Dervenis, Christos AU - Dervenis C LA - eng PT - Journal Article DEP - 20071203 PL - Netherlands TA - Surg Oncol JT - Surgical oncology JID - 9208188 SB - IM MH - Aged MH - Blood Loss, Surgical/*prevention & control MH - Catheter Ablation/*instrumentation MH - Cohort Studies MH - Electrodes MH - Female MH - *Hepatectomy/adverse effects MH - Humans MH - Liver Diseases/etiology/pathology/*surgery MH - Male MH - Middle Aged MH - Retrospective Studies MH - Treatment Outcome EDAT- 2007/12/07 09:00 MHDA- 2008/09/26 09:00 CRDT- 2007/12/07 09:00 PHST- 2007/07/14 00:00 [received] PHST- 2007/09/30 00:00 [revised] PHST- 2007/10/22 00:00 [accepted] PHST- 2007/12/07 09:00 [pubmed] PHST- 2008/09/26 09:00 [medline] PHST- 2007/12/07 09:00 [entrez] AID - S0960-7404(07)00150-8 [pii] AID - 10.1016/j.suronc.2007.10.046 [doi] PST - ppublish SO - Surg Oncol. 2008 Aug;17(2):81-6. doi: 10.1016/j.suronc.2007.10.046. Epub 2007 Dec 3.