PMID- 1806584
OWN - NLM
STAT- MEDLINE
DCOM- 19920508
LR  - 20071115
IS  - 0197-1522 (Print)
IS  - 0197-1522 (Linking)
VI  - 12
IP  - 4
DP  - 1991
TI  - Development of the Abbott MATRIX Aero assay for the measurement of specific IgE.
PG  - 465-85
AB  - An enzyme immunoassay has been developed for the quantitation of specific 
      immunoglobulin E (IgE) in human serum to a panel of allergens. The assay system, 
      called the Abbott MATRIX Aero, includes an instrument, reagents and test cell 
      disposables. Each test cell contains fourteen airborne allergens individually 
      localized on a nitrocellulose solid phase. Individual calibration curves for each 
      allergen are established by the manufacturer and included in barcode form with 
      each test kit. Stable factory calibration eliminates the need to establish a 
      calibration curve with each assay run. The instrument automatically incubates, 
      washes, and reads the test cell and prints each result, which ensures assay 
      reproducibility and provides ease-of-use. Analysis of test results shows good 
      agreement with another in vitro assay for specific IgE. The Abbott MATRIX Aero is 
      a sensitive, reproducible and easy-to-use system for the measurement of specific 
      IgE to a panel of fourteen allergens simultaneously using a single, small volume 
      of serum.
FAU - Lindberg, R E
AU  - Lindberg RE
AD  - Abbott Laboratories, Abbott Park, IL 60064-3500.
FAU - Anawis, M A
AU  - Anawis MA
FAU - Bailey, M
AU  - Bailey M
FAU - Mangat, D
AU  - Mangat D
FAU - Frank, P M
AU  - Frank PM
FAU - Hrusovsky, I G
AU  - Hrusovsky IG
FAU - Hooyman, L
AU  - Hooyman L
FAU - Putterman, C
AU  - Putterman C
FAU - Defreese, J D
AU  - Defreese JD
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Immunoassay
JT  - Journal of immunoassay
JID - 8007167
RN  - 0 (Allergens)
RN  - 0 (Reagent Kits, Diagnostic)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Allergens/immunology
MH  - Antibody Specificity
MH  - Calibration
MH  - Evaluation Studies as Topic
MH  - Humans
MH  - Hypersensitivity, Immediate/*diagnosis
MH  - Immunoglobulin E/*blood/immunology
MH  - Radioallergosorbent Test
MH  - *Reagent Kits, Diagnostic/standards
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1080/01971529108053275 [doi]
PST - ppublish
SO  - J Immunoassay. 1991;12(4):465-85. doi: 10.1080/01971529108053275.