PMID- 18067202
OWN - NLM
STAT- MEDLINE
DCOM- 20080311
LR  - 20071210
IS  - 1107-0625 (Print)
IS  - 1107-0625 (Linking)
VI  - 12
IP  - 4
DP  - 2007 Oct-Dec
TI  - Surgery after induction chemoradiotherapy for non small cell lung cancer: when 
      and why.
PG  - 453-61
AB  - Stages I and II non small cell lung cancer (NSCLC) are primarily treated by 
      anatomic pulmonary resection. Selected patients with stage IIIB disease are still 
      candidates for surgical treatment. Unfortunately most patients with locally 
      advanced NSCLC don't benefit by surgery alone or even by the combination of 
      chemotherapy and radiotherapy. In order to achieve local and distant disease 
      control, which seems to be the cause of failure of the above mentioned 
      treatments, surgery after induction chemoradiotherapy has been proposed. This 
      approach seems to be the state of the art of therapy for these patients improving 
      survival but with eventual increased risks, especially pulmonary and septic 
      complications. This review of previously published studies indicates the 
      important role of this combined treatment in terms of survival and its risks 
      related either to induction treatment or to surgery.
FAU - Koletsis, E N
AU  - Koletsis EN
AD  - Department of Cardiothoracic Surgery, University of Patras, Patras, Greece. 
      ekoletsis@hotmail.com
FAU - Prokakis, C
AU  - Prokakis C
FAU - Apostolakis, E
AU  - Apostolakis E
FAU - Chatzimichalis, A
AU  - Chatzimichalis A
FAU - Dougenis, D
AU  - Dougenis D
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Cyprus
TA  - J BUON
JT  - Journal of B.U.ON. : official journal of the Balkan Union of Oncology
JID - 100883428
SB  - IM
MH  - Carcinoma, Non-Small-Cell Lung/drug therapy/surgery/*therapy
MH  - Combined Modality Therapy
MH  - Female
MH  - Humans
MH  - Lung Neoplasms/drug therapy/surgery/*therapy
MH  - Male
RF  - 72
EDAT- 2007/12/11 09:00
MHDA- 2008/03/12 09:00
CRDT- 2007/12/11 09:00
PHST- 2007/12/11 09:00 [pubmed]
PHST- 2008/03/12 09:00 [medline]
PHST- 2007/12/11 09:00 [entrez]
PST - ppublish
SO  - J BUON. 2007 Oct-Dec;12(4):453-61.