PMID- 18068900 OWN - NLM STAT- MEDLINE DCOM- 20080501 LR - 20220409 IS - 0304-3940 (Print) IS - 0304-3940 (Linking) VI - 431 IP - 1 DP - 2008 Jan 24 TI - Influence of exercise on serum brain-derived neurotrophic factor concentrations in healthy human subjects. PG - 62-5 AB - The effect of short-term exercise (15 min step-exercise) on serum brain-derived neurotrophic factor (BDNF) levels was evaluated in healthy human subjects. Results showed a short-term, significant increase in serum BDNF levels after exercise. Intra-individual differences in serum BDNF levels were remarkably small on the rest day and also when compared to rest values on the day of the exercise test. Inter-individual differences, on the other hand, were larger by comparison. The result of this study supports the need for larger sample size in studies on BDNF changes in psychiatric disorders or psychiatric drug effects. FAU - Tang, Siu Wa AU - Tang SW AD - Department of Psychiatry, University of Hong Kong, Hong Kong. FAU - Chu, Emily AU - Chu E FAU - Hui, Tomy AU - Hui T FAU - Helmeste, Daiga AU - Helmeste D FAU - Law, Cindy AU - Law C LA - eng PT - Journal Article DEP - 20071117 PL - Ireland TA - Neurosci Lett JT - Neuroscience letters JID - 7600130 RN - 0 (Brain-Derived Neurotrophic Factor) SB - IM MH - Adult MH - Brain/*metabolism MH - Brain-Derived Neurotrophic Factor/*blood MH - Depressive Disorder/blood/physiopathology MH - Exercise/*physiology MH - Female MH - Humans MH - Male MH - Physical Fitness/*physiology MH - Sample Size MH - Up-Regulation/*physiology EDAT- 2007/12/11 09:00 MHDA- 2008/05/02 09:00 CRDT- 2007/12/11 09:00 PHST- 2007/07/08 00:00 [received] PHST- 2007/09/16 00:00 [revised] PHST- 2007/11/12 00:00 [accepted] PHST- 2007/12/11 09:00 [pubmed] PHST- 2008/05/02 09:00 [medline] PHST- 2007/12/11 09:00 [entrez] AID - S0304-3940(07)01194-9 [pii] AID - 10.1016/j.neulet.2007.11.019 [doi] PST - ppublish SO - Neurosci Lett. 2008 Jan 24;431(1):62-5. doi: 10.1016/j.neulet.2007.11.019. Epub 2007 Nov 17.