PMID- 18070626
OWN - NLM
STAT- MEDLINE
DCOM- 20080422
LR  - 20191210
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1178
IP  - 1-2
DP  - 2008 Jan 18
TI  - Supported liquid-liquid extraction of the active ingredient 
      (3,4-methylenedioxymethylamphetamine) from ecstasy tablets for isotopic analysis.
PG  - 1-8
AB  - A method was developed for the isolation of 3,4-methylenedioxymethylamphetamine 
      (MDMA) and other active ingredients from illicit ecstasy tablets. The method 
      employed supported liquid extraction (SLE) with cartridges containing a modified 
      form of diatomaceous earth. The method developed was simple and robust and the 
      extract could be analysed directly, by GC-MS, to identify ingredients and reduced 
      in volume for isotope ratio MS analysis of both delta(13)C and delta(15)N. The 
      technique was shown to be highly reproducible, independent of the tablet matrix 
      and considerably faster than existing liquid-liquid extraction methods. 
      Crucially, no significant isotopic fractionation was observed as a result of the 
      extraction process.
FAU - de Korompay, Alanna
AU  - de Korompay A
AD  - Centre for Forensic Science, Department of Pure and Applied Chemistry, University 
      of Strathclyde, Royal College, 204 George Street, Glasgow G1 1XW, UK.
FAU - Hill, Jenny C
AU  - Hill JC
FAU - Carter, James F
AU  - Carter JF
FAU - NicDaeid, Niamh
AU  - NicDaeid N
FAU - Sleeman, Richard
AU  - Sleeman R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071122
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Hallucinogens)
RN  - 0 (Illicit Drugs)
RN  - 0 (Isotopes)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/analysis/*isolation & purification
MH  - Gas Chromatography-Mass Spectrometry/methods
MH  - Hallucinogens/*chemistry
MH  - Illicit Drugs/*chemistry
MH  - Isotopes/*analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*chemistry
MH  - Reproducibility of Results
EDAT- 2007/12/12 09:00
MHDA- 2008/04/23 09:00
CRDT- 2007/12/12 09:00
PHST- 2007/10/04 00:00 [received]
PHST- 2007/11/06 00:00 [revised]
PHST- 2007/11/09 00:00 [accepted]
PHST- 2007/12/12 09:00 [pubmed]
PHST- 2008/04/23 09:00 [medline]
PHST- 2007/12/12 09:00 [entrez]
AID - S0021-9673(07)01958-9 [pii]
AID - 10.1016/j.chroma.2007.11.054 [doi]
PST - ppublish
SO  - J Chromatogr A. 2008 Jan 18;1178(1-2):1-8. doi: 10.1016/j.chroma.2007.11.054. 
      Epub 2007 Nov 22.