PMID- 1807491
OWN - NLM
STAT- MEDLINE
DCOM- 19920520
LR  - 20190918
IS  - 0886-0440 (Print)
IS  - 0886-0440 (Linking)
VI  - 6
IP  - 1 Suppl
DP  - 1991 Mar
TI  - Latissimus dorsi cardiomyoplasty in severe congestive heart failure: the Lyon 
      experience.
PG  - 106-12
AB  - Eleven male patients, New York Heart Association (NYHA) Class III, have undergone 
      cardiomyoplasty (Chachques and Carpentier technique). There were no deaths. Two 
      patients suffered from low cardiac output, one patient suffered a massive aortic 
      bifurcation embolism, and one patient had a Legionella pneumonia. All patients 
      recovered well. The follow-up was 6.9 +/- 2.3 months. One patient had a 
      Cardiomyostimulator Pulse Train Generator failure and had it replaced. The first 
      seven patients were evaluated 6 months after surgery. They all improved (Class 
      II) except for one, who was transplanted. The maximal level of exercise was 
      improved (92 +/- 18 W vs 60 +/- 24 W), as was the heart rate-systolic blood 
      pressure product (30,262 +/- 3,119 vs 19,908 +/- 4,190), mainly due to an 
      increase in systolic blood pressure (200.0 +/- 25.5 vs 141.5 +/- 20.3 mmHg). 
      Echographic parameters, maximal oxygen consumption, left ventricular ejection 
      fraction (LVEF), cardiac index, oxygen arteriovenous difference, and cardiac 
      filling pressures did not change. The left ventricular (LV) angiography always 
      showed good contraction of the latissimus dorsi. A problem needing investigation 
      is the principle of cardiomyoplasty (CMP) itself, as the muscle acts more as a 
      lift than as pincers. Our patients, and patients from other series, improved 
      functionally, and they exercised more. Improvement in survival can be studied 
      only by a randomized clinical trial.
FAU - Delahaye, F
AU  - Delahaye F
AD  - Unite 30, Hopital Cardiovasculaire et Penumologique, Lyon, France.
FAU - Jegaden, O
AU  - Jegaden O
FAU - Montagna, P
AU  - Montagna P
FAU - Desseigne, P
AU  - Desseigne P
FAU - Blanc, P
AU  - Blanc P
FAU - Vedrinne, C
AU  - Vedrinne C
FAU - Touboul, P
AU  - Touboul P
FAU - Saint-Pierre, A
AU  - Saint-Pierre A
FAU - Perinetti, M
AU  - Perinetti M
FAU - Rossi, R
AU  - Rossi R
AU  - et al.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Aged
MH  - Assisted Circulation
MH  - Back/physiology
MH  - Electric Stimulation/methods
MH  - Exercise Test
MH  - Follow-Up Studies
MH  - Heart Failure/mortality/physiopathology/*surgery
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscles/physiology
MH  - Postoperative Complications
MH  - Surgical Flaps/*methods/mortality
EDAT- 1991/03/01 00:00
MHDA- 1991/03/01 00:01
CRDT- 1991/03/01 00:00
PHST- 1991/03/01 00:00 [pubmed]
PHST- 1991/03/01 00:01 [medline]
PHST- 1991/03/01 00:00 [entrez]
AID - 10.1111/jocs.1991.6.1s.106 [doi]
PST - ppublish
SO  - J Card Surg. 1991 Mar;6(1 Suppl):106-12. doi: 10.1111/jocs.1991.6.1s.106.