PMID- 18085730 OWN - NLM STAT- MEDLINE DCOM- 20080610 LR - 20141120 IS - 0315-162X (Print) IS - 0315-162X (Linking) VI - 35 IP - 3 DP - 2008 Mar TI - Relapses in patients with antineutrophil cytoplasmic autoantibody-associated vasculitis: likely to begin with the same organ as initial onset. PG - 448-50 AB - OBJECTIVE: In antineutrophil cytoplasmic antibody-associated vasculitis (AAV), relapses constitute a challenge despite initial good control. Our objective was to investigate whether patients with relapses shared the same initial organ involvement. METHODS: One hundred sixty patients with AAV in our center were investigated. Of these 160, 38 experienced relapse during followup. Clinical and laboratory data were analyzed. RESULTS: Among the 38 patients, there was a total of 55 relapse events, 39 (70.9%) of which had the same initial organ as in the initial onset. CONCLUSION: Relapses in AAV were likely to begin with the same organ as in the initial onset; this facilitates early recognition of relapses. FAU - Chen, Min AU - Chen M AD - Renal Division, Department of Medicine, Peking University First Hospital, Beijing, China. FAU - Yu, Feng AU - Yu F FAU - Zhao, Ming-Hui AU - Zhao MH LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20071215 PL - Canada TA - J Rheumatol JT - The Journal of rheumatology JID - 7501984 RN - 0 (Antibodies, Antineutrophil Cytoplasmic) RN - 0 (Immunosuppressive Agents) SB - IM MH - Adult MH - Aged MH - Antibodies, Antineutrophil Cytoplasmic/immunology MH - Cohort Studies MH - Female MH - Granulomatosis with Polyangiitis/drug therapy/*physiopathology MH - Humans MH - Immunosuppressive Agents/therapeutic use MH - Male MH - Middle Aged MH - Recurrence MH - Remission Induction MH - Survival Analysis EDAT- 2007/12/19 09:00 MHDA- 2008/06/11 09:00 CRDT- 2007/12/19 09:00 PHST- 2007/12/19 09:00 [pubmed] PHST- 2008/06/11 09:00 [medline] PHST- 2007/12/19 09:00 [entrez] AID - 07/13/1222 [pii] PST - ppublish SO - J Rheumatol. 2008 Mar;35(3):448-50. Epub 2007 Dec 15.