PMID- 18086135
OWN - NLM
STAT- MEDLINE
DCOM- 20080507
LR  - 20220419
IS  - 0896-4327 (Print)
IS  - 0896-4327 (Linking)
VI  - 21
IP  - 1
DP  - 2008 Feb
TI  - Fenestrated occluders for treatment of ASD in elderly patients with pulmonary 
      hypertension and/or right heart failure.
PG  - 44-9
AB  - Atrial septal defect (ASD) occlusion in adult patients with advanced age and left 
      or right heart diastolic or systolic heart failure and in patients with pulmonary 
      arterial hypertension bears a considerable risk of deterioration of heart 
      failure. Therefore, we conducted this feasibility trial in 15 ASD patients with 
      pulmonary hypertension and/or right heart failure using a fenestrated Amplatzer 
      septal occluder (AGA Medical Corporation, Golden Valley, MN), allowing an 
      overflow of blood in both directions in case of univentricular diastolic or 
      systolic heart failure. In all patients, the device could be implanted without 
      complications. All symptomatic patients showed an improvement in the New York 
      Heart Association (NYHA) class, and no right or left heart decompensation 
      occurred. On echocardiography, right ventricular end diastolic dimension (RVEDD) 
      and pulmonary artery pressure (PAP) decreased significantly, whereas left 
      ventricular end diastolic dimension (LVEDD) increased. Our series of 15 patients 
      with fenestrated ASD occlusion shows that high-risk ASD occlusion can safely be 
      accomplished with excellent clinical results and without complications by a 
      fenestrated occluder.
FAU - Bruch, Leonhard
AU  - Bruch L
AD  - From the Department of Internal Medicine/Cardiology, Unfallkrankenhaus Berlin 
      Academic Teaching Hospital, Berlin, Germany.
FAU - Winkelmann, Anne
AU  - Winkelmann A
FAU - Sonntag, Steffen
AU  - Sonntag S
FAU - Scherf, Franziska
AU  - Scherf F
FAU - Rux, Sascha
AU  - Rux S
FAU - Grad, Marc O
AU  - Grad MO
FAU - Kleber, Franz X
AU  - Kleber FX
LA  - eng
PT  - Journal Article
DEP - 20071211
PL  - United States
TA  - J Interv Cardiol
JT  - Journal of interventional cardiology
JID - 8907826
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Diastole
MH  - Feasibility Studies
MH  - Female
MH  - Heart Failure/diagnostic imaging/physiopathology/*surgery
MH  - Heart Septal Defects, Atrial/physiopathology/*surgery
MH  - Heart Ventricles/diagnostic imaging/physiopathology
MH  - Hemodynamics
MH  - Humans
MH  - Hypertension, Pulmonary/diagnostic imaging/physiopathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Ultrasonography
EDAT- 2007/12/19 09:00
MHDA- 2008/05/08 09:00
CRDT- 2007/12/19 09:00
PHST- 2007/12/19 09:00 [pubmed]
PHST- 2008/05/08 09:00 [medline]
PHST- 2007/12/19 09:00 [entrez]
AID - JOIC324 [pii]
AID - 10.1111/j.1540-8183.2007.00324.x [doi]
PST - ppublish
SO  - J Interv Cardiol. 2008 Feb;21(1):44-9. doi: 10.1111/j.1540-8183.2007.00324.x. 
      Epub 2007 Dec 11.