PMID- 18092231
OWN - NLM
STAT- MEDLINE
DCOM- 20080327
LR  - 20071219
IS  - 0897-7194 (Print)
IS  - 0897-7194 (Linking)
VI  - 25
IP  - 4
DP  - 2007 Aug
TI  - Roles of transforming growth factor-alpha in mammary development and disease.
PG  - 227-35
AB  - Transforming growth factor-alpha (TGFalpha) is a member of the epidermal growth 
      factor (EGF) family. Expression of TGFalpha is highly regulated in response to 
      exogenous cellular signals including cytokines and other growth factors. The 
      growth factor has been found to be indispensable for proper development of many 
      tissues and organs. TGFalpha has also been implicated in numerous disease states 
      including forms of breast cancer. This minireview summarizes the basic biology of 
      TGFalpha and its actions during normal and pathogenic development of the mammary 
      epithelium.
FAU - Booth, Brian W
AU  - Booth BW
AD  - Mammary Biology and Tumorigenesis Laboratory, National Cancer Institute, National 
      Institutes of Health, Bethesda, MD, USA.
FAU - Smith, Gilbert H
AU  - Smith GH
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Growth Factors
JT  - Growth factors (Chur, Switzerland)
JID - 9000468
RN  - 0 (Transforming Growth Factor alpha)
SB  - IM
MH  - Animals
MH  - Disease/etiology
MH  - Humans
MH  - Mammary Glands, Animal/embryology/*growth & development
MH  - Mice
MH  - Neoplasms/*etiology
MH  - Transforming Growth Factor alpha/*physiology
RF  - 95
EDAT- 2007/12/20 09:00
MHDA- 2008/03/28 09:00
CRDT- 2007/12/20 09:00
PHST- 2007/12/20 09:00 [pubmed]
PHST- 2008/03/28 09:00 [medline]
PHST- 2007/12/20 09:00 [entrez]
AID - 788628514 [pii]
AID - 10.1080/08977190701750698 [doi]
PST - ppublish
SO  - Growth Factors. 2007 Aug;25(4):227-35. doi: 10.1080/08977190701750698.