PMID- 18097711
OWN - NLM
STAT- MEDLINE
DCOM- 20080617
LR  - 20211020
IS  - 0770-3198 (Print)
IS  - 0770-3198 (Linking)
VI  - 27
IP  - 4
DP  - 2008 Apr
TI  - A cross-sectional study of 130 Brazilian patients with Crohn's disease and 
      ulcerative colitis: analysis of articular and ophthalmologic manifestations.
PG  - 503-9
AB  - This is a cross-sectional study that analyzed the pattern and frequency of 
      articular and ophthalmologic manifestations in patients with Crohn's disease (CD) 
      and ulcerative colitis (UC), with or without signs of active bowel inflammation. 
      One hundred and thirty consecutive patients with CD (n = 71) and UC (n = 59) were 
      examined. Simple X-rays of lumbar spine, sacroiliac joints, and calcaneal bone 
      were performed and human leukocyte antigen (HLA)-B27 was typed. Joint 
      manifestations occurred in 41 (31.5%) patients, 27 (38%) with CD and 14 (23.7%) 
      with UC. Peripheral involvement occurred in 22 patients, axial involvement in 
      five, and mixed involvement in 14. The most frequently involved joints were knees 
      (56.1%), ankles (29.3%), and hips (29.3%), while the predominant pattern was 
      oligoarticular (84.6%) and asymmetrical (65.6%). Enthesitis was identified in 
      seven (5.4%) patients and inflammatory lumbar pain in 13 (10%). Eight of these 
      patients fulfilled the diagnostic criteria for ankylosing spondylitis (6.2%). 
      Radiographic sacroiliitis occurred in 12 patients (9.2%). Ocular abnormalities 
      were present in six patients (6.2%), and HLA-B27 was positive in five (5.8%). In 
      conclusion, the articular manifestations in the present study were predominantly 
      oligoarticular and asymmetric, with a low frequency of ophthalmologic involvement 
      and positive HLA-B27.
FAU - Lanna, Cristina Costa Duarte
AU  - Lanna CC
AD  - Unit of Rheumatology, Department of Locomotor System, Federal University of Minas 
      Gerais, Belo Horizonte, Brazil. lanna@medicina.ufmg.br
FAU - Ferrari, Maria de Lourdes Abreu
AU  - Ferrari Mde L
FAU - Rocha, Sidney Lemos
AU  - Rocha SL
FAU - Nascimento, Evaldo
AU  - Nascimento E
FAU - de Carvalho, Marco Antonio Parreiras
AU  - de Carvalho MA
FAU - da Cunha, Aloisio Sales
AU  - da Cunha AS
LA  - eng
PT  - Journal Article
DEP - 20071221
PL  - Germany
TA  - Clin Rheumatol
JT  - Clinical rheumatology
JID - 8211469
RN  - 0 (HLA-B27 Antigen)
SB  - IM
MH  - Adult
MH  - Ankle Joint/diagnostic imaging/physiopathology
MH  - Brazil
MH  - Colitis, Ulcerative/*complications/diagnosis/immunology
MH  - Crohn Disease/*complications/diagnosis/immunology
MH  - Cross-Sectional Studies
MH  - Eye Diseases/diagnosis/*etiology/immunology
MH  - Female
MH  - HLA-B27 Antigen/blood
MH  - Hip Joint/diagnostic imaging/physiopathology
MH  - Humans
MH  - Knee Joint/diagnostic imaging/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Radiography
MH  - Sacroiliac Joint/diagnostic imaging
MH  - Spondylarthropathies/diagnosis/*etiology/immunology
EDAT- 2007/12/22 09:00
MHDA- 2008/06/18 09:00
CRDT- 2007/12/22 09:00
PHST- 2007/09/03 00:00 [received]
PHST- 2007/11/09 00:00 [accepted]
PHST- 2007/11/07 00:00 [revised]
PHST- 2007/12/22 09:00 [pubmed]
PHST- 2008/06/18 09:00 [medline]
PHST- 2007/12/22 09:00 [entrez]
AID - 10.1007/s10067-007-0797-5 [doi]
PST - ppublish
SO  - Clin Rheumatol. 2008 Apr;27(4):503-9. doi: 10.1007/s10067-007-0797-5. Epub 2007 
      Dec 21.