PMID- 18157638
OWN - NLM
STAT- MEDLINE
DCOM- 20080828
LR  - 20181113
IS  - 0163-2116 (Print)
IS  - 0163-2116 (Linking)
VI  - 53
IP  - 8
DP  - 2008 Aug
TI  - Response to hepatitis B vaccination in patients with celiac disease.
PG  - 2156-9
AB  - Abnormal immune response to gliadin, genetic, and environmental factors play a 
      role in the pathogenesis of celiac disease (CD). Non-responsiveness to hepatitis 
      B virus (HBV) vaccination is related to genetic features. Certain human leukocyte 
      antigen (HLA) genotypes are more prevalent among non-responders to HBV 
      vaccination. There is also a strong relationship between CD and these HLA 
      genotypes. This study investigates the relationship between CD and 
      non-responsiveness to HBV vaccination, with an emphasis on genotypic 
      co-incidence. No statistically significant difference was noted between the ages 
      and gender of CD patients and control subjects. Baseline serum IgA, IgM, and IgG 
      levels of all CD patients were normal. Responsiveness to HBV vaccination was 
      observed in 17 (68%) CD patients and all (100%) control subjects (P = 0.006). In 
      conclusion, CD should also be sought in unresponders to HBV vaccine who are not 
      immunosuppressed.
FAU - Ahishali, Emel
AU  - Ahishali E
AD  - Department of Gastroenterohepatology, Istanbul Faculty of Medicine, Istanbul 
      University, Capa, Istanbul, Turkey. emelahishali@yahoo.com
FAU - Boztas, Gungor
AU  - Boztas G
FAU - Akyuz, Filiz
AU  - Akyuz F
FAU - Ibrisim, Duygu
AU  - Ibrisim D
FAU - Poturoglu, Sule
AU  - Poturoglu S
FAU - Pinarbasi, Binnur
AU  - Pinarbasi B
FAU - Ozdil, Sadakat
AU  - Ozdil S
FAU - Mungan, Zeynel
AU  - Mungan Z
LA  - eng
PT  - Controlled Clinical Trial
PT  - Journal Article
DEP - 20071220
PL  - United States
TA  - Dig Dis Sci
JT  - Digestive diseases and sciences
JID - 7902782
RN  - 0 (Autoantibodies)
RN  - 0 (HLA Antigens)
RN  - 0 (Hepatitis B Antibodies)
RN  - 0 (Hepatitis B Vaccines)
SB  - IM
MH  - Adult
MH  - Autoantibodies/blood
MH  - Celiac Disease/genetics/*immunology
MH  - Female
MH  - Genotype
MH  - HLA Antigens/genetics/immunology
MH  - Hepatitis B Antibodies/*blood
MH  - Hepatitis B Vaccines/*immunology
MH  - Humans
MH  - Immunization Schedule
MH  - Male
MH  - Middle Aged
MH  - Treatment Failure
EDAT- 2007/12/25 09:00
MHDA- 2008/08/30 09:00
CRDT- 2007/12/25 09:00
PHST- 2007/09/21 00:00 [received]
PHST- 2007/11/09 00:00 [accepted]
PHST- 2007/12/25 09:00 [pubmed]
PHST- 2008/08/30 09:00 [medline]
PHST- 2007/12/25 09:00 [entrez]
AID - 10.1007/s10620-007-0128-3 [doi]
PST - ppublish
SO  - Dig Dis Sci. 2008 Aug;53(8):2156-9. doi: 10.1007/s10620-007-0128-3. Epub 2007 Dec 
      20.