PMID- 18182261
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20080507
LR  - 20080414
IS  - 1872-6283 (Electronic)
IS  - 0379-0738 (Linking)
VI  - 177
IP  - 2-3
DP  - 2008 May 20
TI  - Drug intelligence based on organic impurities in illicit MA samples.
PG  - 153-61
LID - 10.1016/j.forsciint.2007.11.013 [doi]
AB  - One major objective of the European project "Collaborative Harmonisation of 
      Methods for Profiling of Amphetamine Type Stimulants" (CHAMP), funded by the 
      sixth framework programme of the European Commission, consisted of the 
      harmonisation of a gas chromatography/mass spectrometry (GC/MS) method for the 
      analysis of organic impurities found in illicit methamphetamine (MA) samples in a 
      drug intelligence perspective. Statistical analysis provided a selection of 
      pertinent variables among the 43 organic impurities identified in the 
      chromatograms. As for the 3,4-MethyleneDioxyMethAmphetamine (MDMA) study, 
      correlation coefficients were used as a discrimination tool between populations 
      of linked samples (from the same seizure) and unlinked samples (from different 
      seizures). It was also shown that correlation measurements based on Pearson and 
      cosine functions applied to the data pre-treated by normalisation to the sum of 
      peak responses followed by the square root provided excellent discrimination 
      between the two populations. The organic impurities profiling method was proved 
      to be relevant for the characterization of samples from different seizures and 
      their synthesis route patterns.
FAU - Dujourdy, L
AU  - Dujourdy L
AD  - Laboratoire Police Scientifique de Lyon, 31 Avenue Franklin Roosevelt, 69134 
      Ecully, France. Laurence.Dujourdy@interieur.gouv.fr
FAU - Dufey, V
AU  - Dufey V
FAU - Besacier, F
AU  - Besacier F
FAU - Miano, N
AU  - Miano N
FAU - Marquis, R
AU  - Marquis R
FAU - Lock, E
AU  - Lock E
FAU - Aalberg, L
AU  - Aalberg L
FAU - Dieckmann, S
AU  - Dieckmann S
FAU - Zrcek, F
AU  - Zrcek F
FAU - Bozenko, J S Jr
AU  - Bozenko JS Jr
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20080107
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
EDAT- 2008/01/10 09:00
MHDA- 2008/01/10 09:01
CRDT- 2008/01/10 09:00
PHST- 2007/06/15 00:00 [received]
PHST- 2007/11/21 00:00 [revised]
PHST- 2007/11/23 00:00 [accepted]
PHST- 2008/01/10 09:00 [pubmed]
PHST- 2008/01/10 09:01 [medline]
PHST- 2008/01/10 09:00 [entrez]
AID - S0379-0738(07)00829-8 [pii]
AID - 10.1016/j.forsciint.2007.11.013 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2008 May 20;177(2-3):153-61. doi: 
      10.1016/j.forsciint.2007.11.013. Epub 2008 Jan 7.