PMID- 18186582 OWN - NLM STAT- MEDLINE DCOM- 20080327 LR - 20080111 IS - 0192-415X (Print) IS - 0192-415X (Linking) VI - 35 IP - 6 DP - 2007 TI - Serum IgG, IgA, IgM, and IgE levels after electroacupuncture and diet therapy in obese women. PG - 955-65 AB - We investigated the effect of acupuncture therapy on obese women's body weight and peripheral blood levels of serum immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), and immunoglobulin E (IgE). Sixty-three healthy women were assigned into 3 groups: placebo electroacupuncture (n = 13; mean age, 40.5 +/- 4.2 years; body mass index [BMI], 33.5 +/- 4.2), diet restriction (n = 23; mean age, 42.9 +/- 4.0 years; BMI, 34.6 +/- 2.9), and electroacupuncture (n = 24; mean age, 40.1 +/- 5.9 years; BMI, 33.9 +/- 2.7). Electroacupuncture was applied to the Hunger and Shen Men ear points and to the LI 4, LI 11, St 36, St 44, and Ren 6 body points for 30 min once daily for 20 days. A restricted diet of 1400 kilocalories was given to participants in all 3 groups for 20 days. Weight was lost significantly in subjects in the electroacupuncture group compared to those in the diet restriction and placebo electroacupuncture groups (p < 0.000, Tukey test). Modulations in serum IgG (p < 0.001) were apparent in women treated with electroacupuncture compared with women treated with placebo electroacupuncture and restricted diet only. No significant changes were seen in serum IgA, IgM, and IgE levels among the 3 groups. Our results suggest that electroacupuncture can be effectively used to treat obesity. We also observed a modulating effect of serum IgG, which is associated with weight loss, in patients in the electroacupuncture group. FAU - Cabioglu, Mehmet T AU - Cabioglu MT AD - Department of Physiology, Medical Faculty, Baskent University, Ankara, Turkey. tugcab@yahoo.com FAU - Ergene, Neyhan AU - Ergene N FAU - Surucu, H Selcuk AU - Surucu HS FAU - Celik, H Hamdi AU - Celik HH FAU - Findik, Duygu AU - Findik D LA - eng PT - Clinical Trial PT - Comparative Study PT - Journal Article PL - Singapore TA - Am J Chin Med JT - The American journal of Chinese medicine JID - 7901431 RN - 0 (Immunoglobulin A) RN - 0 (Immunoglobulin G) RN - 0 (Immunoglobulin M) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Body Weight/physiology MH - Diet Therapy/methods MH - Electroacupuncture/*methods MH - Female MH - Humans MH - Immunoglobulin A/*blood MH - Immunoglobulin E/*blood MH - Immunoglobulin G/*blood MH - Immunoglobulin M/*blood MH - Middle Aged MH - Obesity/blood/*diet therapy/immunology MH - Weight Loss/physiology EDAT- 2008/01/12 09:00 MHDA- 2008/03/28 09:00 CRDT- 2008/01/12 09:00 PHST- 2008/01/12 09:00 [pubmed] PHST- 2008/03/28 09:00 [medline] PHST- 2008/01/12 09:00 [entrez] AID - S0192415X07005429 [pii] AID - 10.1142/S0192415X07005429 [doi] PST - ppublish SO - Am J Chin Med. 2007;35(6):955-65. doi: 10.1142/S0192415X07005429.