PMID- 18188442
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20220410
IS  - 1723-8617 (Print)
IS  - 1723-8617 (Linking)
VI  - 6
IP  - 3
DP  - 2007 Oct
TI  - Lifetime prevalence and age-of-onset distributions of mental disorders in the 
      World Health Organization's World Mental Health Survey Initiative.
PG  - 168-76
AB  - Data are presented on the lifetime prevalence, projected lifetime risk, and 
      age-of-onset distributions of mental disorders in the World Health Organization 
      (WHO)'s World Mental Health (WMH) Surveys. Face-to-face community surveys were 
      conducted in seventeen countries in Africa, Asia, the Americas, Europe, and the 
      Middle East. The combined numbers of respondents were 85,052. Lifetime 
      prevalence, projected lifetime risk, and age of onset of DSM-IV disorders were 
      assessed with the WHO Composite International Diagnostic Interview (CIDI), a 
      fully-structured lay administered diagnostic interview. Survival analysis was 
      used to estimate lifetime risk. Median and inter-quartile range (IQR) of age of 
      onset is very early for some anxiety disorders (7-14, IQR: 8-11) and impulse 
      control disorders (7-15, IQR: 11-12). The age-of-onset distribution is later for 
      mood disorders (29-43, IQR: 35-40), other anxiety disorders (24-50, IQR: 31-41), 
      and substance use disorders (18-29, IQR: 21-26). Median and IQR lifetime 
      prevalence estimates are: anxiety disorders 4.8-31.0% (IQR: 9.9-16.7%), mood 
      disorders 3.3-21.4% (IQR: 9.8-15.8%), impulse control disorders 0.3-25.0% (IQR: 
      3.1-5.7%), substance use disorders 1.3-15.0% (IQR: 4.8-9.6%), and any disorder 
      12.0-47.4% (IQR: 18.1-36.1%). Projected lifetime risk is proportionally between 
      17% and 69% higher than estimated lifetime prevalence (IQR: 28-44%), with the 
      highest ratios in countries exposed to sectarian violence (Israel, Nigeria, and 
      South Africa), and a general tendency for projected risk to be highest in recent 
      cohorts in all countries. These results document clearly that mental disorders 
      are commonly occurring. As many mental disorders begin in childhood or 
      adolescents, interventions aimed at early detection and treatment might help 
      reduce the persistence or severity of primary disorders and prevent the 
      subsequent onset of secondary disorders.
FAU - Kessler, Ronald C
AU  - Kessler RC
AD  - Department of Health Care Policy, Harvard Medical School, 180 Longwood Avenue, 
      Boston, MA 02115, USA;
FAU - Angermeyer, Matthias
AU  - Angermeyer M
FAU - Anthony, James C
AU  - Anthony JC
FAU - DE Graaf, Ron
AU  - DE Graaf R
FAU - Demyttenaere, Koen
AU  - Demyttenaere K
FAU - Gasquet, Isabelle
AU  - Gasquet I
FAU - DE Girolamo, Giovanni
AU  - DE Girolamo G
FAU - Gluzman, Semyon
AU  - Gluzman S
FAU - Gureje, Oye
AU  - Gureje O
FAU - Haro, Josep Maria
AU  - Haro JM
FAU - Kawakami, Norito
AU  - Kawakami N
FAU - Karam, Aimee
AU  - Karam A
FAU - Levinson, Daphna
AU  - Levinson D
FAU - Medina Mora, Maria Elena
AU  - Medina Mora ME
FAU - Oakley Browne, Mark A
AU  - Oakley Browne MA
FAU - Posada-Villa, Jose
AU  - Posada-Villa J
FAU - Stein, Dan J
AU  - Stein DJ
FAU - Adley Tsang, Cheuk Him
AU  - Adley Tsang CH
FAU - Aguilar-Gaxiola, Sergio
AU  - Aguilar-Gaxiola S
FAU - Alonso, Jordi
AU  - Alonso J
FAU - Lee, Sing
AU  - Lee S
FAU - Heeringa, Steven
AU  - Heeringa S
FAU - Pennell, Beth-Ellen
AU  - Pennell BE
FAU - Berglund, Patricia
AU  - Berglund P
FAU - Gruber, Michael J
AU  - Gruber MJ
FAU - Petukhova, Maria
AU  - Petukhova M
FAU - Chatterji, Somnath
AU  - Chatterji S
FAU - Ustun, T Bedirhan
AU  - Ustun TB
LA  - eng
GR  - R03 TW006481/TW/FIC NIH HHS/United States
GR  - R01 MH069864/MH/NIMH NIH HHS/United States
GR  - R01 MH061905/MH/NIMH NIH HHS/United States
GR  - K05 DA015799/DA/NIDA NIH HHS/United States
GR  - U01 MH060220/MH/NIMH NIH HHS/United States
GR  - R01 MH070884/MH/NIMH NIH HHS/United States
GR  - R01 MH059575/MH/NIMH NIH HHS/United States
GR  - R13 MH066849/MH/NIMH NIH HHS/United States
PT  - Journal Article
PL  - Italy
TA  - World Psychiatry
JT  - World psychiatry : official journal of the World Psychiatric Association (WPA)
JID - 101189643
PMC - PMC2174588
OTO - NOTNLM
OT  - Mental disorders
OT  - age-of-onset distribution
OT  - lifetime prevalence
OT  - projected lifetime risk
EDAT- 2008/01/12 09:00
MHDA- 2008/01/12 09:01
PMCR- 2007/10/01
CRDT- 2008/01/12 09:00
PHST- 2008/01/12 09:00 [pubmed]
PHST- 2008/01/12 09:01 [medline]
PHST- 2008/01/12 09:00 [entrez]
PHST- 2007/10/01 00:00 [pmc-release]
PST - ppublish
SO  - World Psychiatry. 2007 Oct;6(3):168-76.