PMID- 18189004
OWN - NLM
STAT- MEDLINE
DCOM- 20080124
LR  - 20191110
IS  - 1530-7026 (Print)
IS  - 1530-7026 (Linking)
VI  - 7
IP  - 4
DP  - 2007 Dec
TI  - Regions of the MPFC differentially tuned to social and nonsocial affective 
      evaluation.
PG  - 309-16
AB  - The medial prefrontal cortex (MPFC) reliably activates in social cognition and 
      reward tasks. This study locates distinct areas for each. Participants made 
      evaluative (positive/negative) or social (person/not a person) judgments of 
      pictured positive or negative people and objects in a slow event-related design. 
      Activity in an anterior rostral region (arMPFC) was significantly greater for 
      positive than for negative persons but did not show a valence effect for objects, 
      and this was true regardless of the judgment task. This suggests that the arMPFC 
      is tuned to social valence. Interestingly, however, no regions of the MPFC were 
      found to be responsive to social information independently of valence. A 
      region-of-interest analysis of the para-anterior cingulate cortex (pACC), 
      previously implicated in reward processing, demonstrated sensitivity to the 
      valence of all stimuli, whether persons or objects, across tasks. Affective 
      evaluation may be a general function of the MPFC, with some regions being tuned 
      to more specific domains of information (e.g., social) than are others.
FAU - Harris, Lasana T
AU  - Harris LT
AD  - Princeton University, Princeton, New Jersey, USA. lasana@nyu.edu
FAU - McClure, Samuel M
AU  - McClure SM
FAU - van den Bos, Wouter
AU  - van den Bos W
FAU - Cohen, Jonathan D
AU  - Cohen JD
FAU - Fiske, Susan T
AU  - Fiske ST
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Cogn Affect Behav Neurosci
JT  - Cognitive, affective & behavioral neuroscience
JID - 101083946
SB  - IM
MH  - Adult
MH  - Affect/*physiology
MH  - Cognition/physiology
MH  - Data Interpretation, Statistical
MH  - Echo-Planar Imaging
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Photic Stimulation
MH  - Prefrontal Cortex/*physiology
MH  - Reward
MH  - Social Environment
MH  - *Social Perception
EDAT- 2008/01/15 09:00
MHDA- 2008/01/25 09:00
CRDT- 2008/01/15 09:00
PHST- 2008/01/15 09:00 [pubmed]
PHST- 2008/01/25 09:00 [medline]
PHST- 2008/01/15 09:00 [entrez]
AID - 10.3758/cabn.7.4.309 [doi]
PST - ppublish
SO  - Cogn Affect Behav Neurosci. 2007 Dec;7(4):309-16. doi: 10.3758/cabn.7.4.309.