PMID- 18190993
OWN - NLM
STAT- MEDLINE
DCOM- 20080512
LR  - 20131121
IS  - 0168-1605 (Print)
IS  - 0168-1605 (Linking)
VI  - 122
IP  - 1-2
DP  - 2008 Feb 29
TI  - Antimycotoxigenic characteristics of Rosmarinus officinalis and Trachyspermum 
      copticum L. essential oils.
PG  - 135-9
LID - 10.1016/j.ijfoodmicro.2007.11.048 [doi]
AB  - Aflatoxin B1 (AFB1) is a highly toxic and carcinogenic metabolite produced by 
      Aspergillus species on food and agricultural commodities. Natural products may 
      regulate the cellular effects of aflatoxins and evidence suggests that aromatic 
      organic compounds of spices can control the production of aflatoxins. With a view 
      to controlling aflatoxin production, the essential oils from Rosmarinus 
      officinalis and Trachyspermum copticum L. were obtained by hydrodistillation. 
      Antifungal activities of the oils were studied with special reference to the 
      inhibition of Aspergillus parasiticus growth and aflatoxin production. Minimal 
      inhibitory (MIC) and minimal fungicidal (MFC) concentrations of the oils were 
      determined. T. copticum L. oil showed a stronger inhibitory effect than R. 
      officinalis on the growth of A. parasiticus. Aflatoxin production was inhibited 
      at 450 ppm of both oils with that of R. officinalis being stronger inhibitor. The 
      oils were analyzed by GC and GC/MS. The major components of R. officinalis and T. 
      copticum L. oils were Piperitone (23.65%), alpha-pinene (14.94%), Limonene 
      (14.89%), 1,8-Cineole (7.43%) and Thymol (37.2%), P-Cymene (32.3%), 
      gamma-Terpinene (27.3%) respectively. It is concluded that the essential oils 
      could be safely used as preservative materials on some kinds of foods to protect 
      them from toxigenic fungal infections.
FAU - Rasooli, Iraj
AU  - Rasooli I
AD  - Department of Biology, Shahed University, Tehran-Qom Express Way, Opposite Imam 
      Khomeini's shrine, Tehran-3319118651, Iran. rasooli@shahed.ac.ir
FAU - Fakoor, Mohammad Hadi
AU  - Fakoor MH
FAU - Yadegarinia, Davod
AU  - Yadegarinia D
FAU - Gachkar, Latif
AU  - Gachkar L
FAU - Allameh, Abdolamir
AU  - Allameh A
FAU - Rezaei, Mohammad Bagher
AU  - Rezaei MB
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20071129
PL  - Netherlands
TA  - Int J Food Microbiol
JT  - International journal of food microbiology
JID - 8412849
RN  - 0 (Antifungal Agents)
RN  - 0 (Food Preservatives)
RN  - 0 (Oils, Volatile)
RN  - 9N2N2Y55MH (Aflatoxin B1)
SB  - IM
MH  - Aflatoxin B1/biosynthesis
MH  - Antifungal Agents/*pharmacology
MH  - Apiaceae/*chemistry
MH  - Aspergillus/*drug effects/growth & development/metabolism
MH  - Colony Count, Microbial
MH  - Dose-Response Relationship, Drug
MH  - Food Preservation/methods
MH  - Food Preservatives/pharmacology
MH  - Microbial Sensitivity Tests
MH  - Oils, Volatile/*pharmacology
MH  - Rosmarinus/*chemistry
EDAT- 2008/01/15 09:00
MHDA- 2008/05/13 09:00
CRDT- 2008/01/15 09:00
PHST- 2007/06/22 00:00 [received]
PHST- 2007/10/01 00:00 [revised]
PHST- 2007/11/19 00:00 [accepted]
PHST- 2008/01/15 09:00 [pubmed]
PHST- 2008/05/13 09:00 [medline]
PHST- 2008/01/15 09:00 [entrez]
AID - S0168-1605(07)00635-6 [pii]
AID - 10.1016/j.ijfoodmicro.2007.11.048 [doi]
PST - ppublish
SO  - Int J Food Microbiol. 2008 Feb 29;122(1-2):135-9. doi: 
      10.1016/j.ijfoodmicro.2007.11.048. Epub 2007 Nov 29.