PMID- 18214792 OWN - NLM STAT- MEDLINE DCOM- 20080228 LR - 20111117 IS - 0882-0538 (Print) IS - 0882-0538 (Linking) VI - 23 IP - 1 DP - 2008 Jan-Feb TI - Genetics of birdshot chorioretinopathy. PG - 53-7 LID - 10.1080/08820530701745231 [doi] AB - Birdshot chorioretinopathy is a bilateral, posterior uveitis that affects primarily Caucasians. Although the genetic basis of disease is not completely understood, certain factors are known, such as the strong association with human leukocyte antigen (HLA)-A29. However, given the prevalence of the HLA-A29 allele in the general population, if it were the only factor required for disease, many more people would have birdshot chorioretinopathy. It has been suggested that some environmental factor may trigger this disease entity in those who are genetically predisposed based on inheritance of the HLA-A29 allele. FAU - Wee, Raymond AU - Wee R AD - Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA. FAU - Papaliodis, George AU - Papaliodis G LA - eng PT - Journal Article PT - Review PL - England TA - Semin Ophthalmol JT - Seminars in ophthalmology JID - 8610759 RN - 0 (HLA-A Antigens) RN - 0 (HLA-A29 antigen) RN - 0 (HLA-B Antigens) RN - 0 (HLA-B12 antigen) SB - IM MH - Animals MH - Autoimmune Diseases/genetics MH - HLA-A Antigens/genetics MH - HLA-B Antigens/genetics MH - Humans MH - Models, Animal MH - Uveitis/genetics MH - Uveitis, Posterior/*genetics RF - 26 EDAT- 2008/01/25 09:00 MHDA- 2008/02/29 09:00 CRDT- 2008/01/25 09:00 PHST- 2008/01/25 09:00 [pubmed] PHST- 2008/02/29 09:00 [medline] PHST- 2008/01/25 09:00 [entrez] AID - 789914940 [pii] AID - 10.1080/08820530701745231 [doi] PST - ppublish SO - Semin Ophthalmol. 2008 Jan-Feb;23(1):53-7. doi: 10.1080/08820530701745231.