PMID- 18217974 OWN - NLM STAT- MEDLINE DCOM- 20090309 LR - 20181030 IS - 1525-1438 (Electronic) IS - 1048-891X (Linking) VI - 18 IP - 6 DP - 2008 Nov-Dec TI - Primary fallopian tube carcinoma associated with ovulation induction; a case report. PG - 1360-3 LID - 10.1111/j.1525-1438.2007.01170.x [doi] AB - The potential relationship between ovulation induction and gynecological cancer has been raised recently. Primary fallopian tube carcinoma (PFTC) is an uncommon malignancy, not previously associated with fertility drugs use. We describe a case of a 38-year-old woman with primary infertility and a history of three ovulation inductions with gonadotropin-releasing hormone agonist and gonadotrophins, referred for treatment of bilateral ovarian cysts, which were discovered in the beginning of the last cycle. During laparotomy, bilateral adnexal masses were identified, presumed to be of ovarian origin, and total abdominal hysterectomy, bilateral salpingo-oophorectomy, infracolic omentectomy, and retroperitoneal lymph nodes sampling were performed. Histologic examination showed a primary right fallopian tube endometrioid adenocarcinoma and bilateral adnexal endometriosis. Surgery was followed by six cycles of combination chemotherapy using paclitaxel and carboplatin without significant complications. Although evidence of a direct causal link between ovarian stimulation and PFTC does not yet exist, this case highlights the importance for careful evaluation of all discovered adnexal masses in women undergoing ovulation induction treatment. FAU - Deliveliotou, A AU - Deliveliotou A AD - 2nd Department of Obstetrics and Gynaecology, Aretaieion Hospital, University of Athens Medical School, Athens, Greece. kdeliveliotou@hotmail.com FAU - Hassiakos, D AU - Hassiakos D FAU - Fotiou, S AU - Fotiou S FAU - Karvouni, E AU - Karvouni E FAU - Creatsas, G AU - Creatsas G LA - eng PT - Case Reports PT - Journal Article DEP - 20080122 PL - England TA - Int J Gynecol Cancer JT - International journal of gynecological cancer : official journal of the International Gynecological Cancer Society JID - 9111626 SB - IM MH - Adult MH - Fallopian Tube Neoplasms/*pathology MH - Female MH - Humans MH - *Ovulation Induction EDAT- 2008/01/26 09:00 MHDA- 2009/03/10 09:00 CRDT- 2008/01/26 09:00 PHST- 2008/01/26 09:00 [pubmed] PHST- 2009/03/10 09:00 [medline] PHST- 2008/01/26 09:00 [entrez] AID - IJG1170 [pii] AID - 10.1111/j.1525-1438.2007.01170.x [doi] PST - ppublish SO - Int J Gynecol Cancer. 2008 Nov-Dec;18(6):1360-3. doi: 10.1111/j.1525-1438.2007.01170.x. Epub 2008 Jan 22.