PMID- 18222250
OWN - NLM
STAT- MEDLINE
DCOM- 20080311
LR  - 20161124
IS  - 1552-6259 (Electronic)
IS  - 0003-4975 (Linking)
VI  - 85
IP  - 2
DP  - 2008 Feb
TI  - Long-term results of coronary artery bypass grafting in patients with left 
      ventricular dysfunction.
PG  - 488-93
LID - 10.1016/j.athoracsur.2007.09.010 [doi]
AB  - BACKGROUND: In this prospective study, we investigated the determinants of 
      long-term outcome, symptoms, and left ventricular function after coronary artery 
      bypass grafting in patients with a moderate to severely decreased left 
      ventricular ejection fraction. METHODS: Between 1997 and 1998, 75 consecutive 
      patients with moderate to severe left ventricular dysfunction underwent coronary 
      artery bypass grafting procedures. The operative mortality rate was 4.0%, and the 
      72 survivors were monitored for 8 years. The end points were mortality, 
      symptomatic status (New York Heart Association [NYHA] functional class), and left 
      ventricular function. RESULTS: The total survival rate after 8 years was 89.3%. 
      During follow-up, 8 patients died. Death was attributed to a cardiac cause in 5 
      patients and to a noncardiac cause in 3. There was no statistically significant 
      difference between preoperative and late postoperative NYHA functional class, 
      despite a statistically significant improvement that persisted for up to 4 years 
      after CABG. The results of echocardiography showed a statistically significant 
      improvement in the left ventricular ejection fraction (from 0.322 +/- 0.06 
      preoperatively to 0.463 +/- 0.02 at follow-up, p < 0.001). Multivariate analysis 
      revealed that the left ventricular end-systolic volume index, the presence of 
      angina pectoris, and absence of symptoms of congestive heart failure were 
      preoperative indicators of freedom from heart failure after coronary operations 
      (p < 0.05). CONCLUSIONS: Coronary artery bypass grafting for patients with 
      moderate-to-severe left ventricular dysfunction is associated with acceptable 
      long-term results. The left ventricular end-systolic volume index is a simple 
      noninvasive method to aid in the preoperative decision making in such patients.
FAU - Soliman Hamad, Mohamed A
AU  - Soliman Hamad MA
AD  - Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The 
      Netherlands. aasmsn@cze.nl
FAU - Tan, M Erwin S H
AU  - Tan ME
FAU - van Straten, Albert H M
AU  - van Straten AH
FAU - van Zundert, Andre A J
AU  - van Zundert AA
FAU - Schonberger, Jacques P A M
AU  - Schonberger JP
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Ann Thorac Surg
JT  - The Annals of thoracic surgery
JID - 15030100R
SB  - IM
MH  - Aged
MH  - Cardiopulmonary Bypass/methods
MH  - *Cause of Death
MH  - Coronary Angiography
MH  - Coronary Artery Bypass/methods/*mortality
MH  - Coronary Stenosis/*complications/diagnostic imaging/surgery
MH  - Echocardiography, Doppler
MH  - Female
MH  - Follow-Up Studies
MH  - Hospital Mortality/trends
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Postoperative Complications/mortality
MH  - Preoperative Care/methods
MH  - Probability
MH  - Prospective Studies
MH  - Risk Assessment
MH  - Severity of Illness Index
MH  - Stroke Volume
MH  - Survival Analysis
MH  - Time Factors
MH  - Treatment Outcome
MH  - Ventricular Dysfunction, Left/*complications/diagnostic imaging
EDAT- 2008/01/29 09:00
MHDA- 2008/03/12 09:00
CRDT- 2008/01/29 09:00
PHST- 2007/07/17 00:00 [received]
PHST- 2007/09/07 00:00 [revised]
PHST- 2007/09/10 00:00 [accepted]
PHST- 2008/01/29 09:00 [pubmed]
PHST- 2008/03/12 09:00 [medline]
PHST- 2008/01/29 09:00 [entrez]
AID - S0003-4975(07)01865-6 [pii]
AID - 10.1016/j.athoracsur.2007.09.010 [doi]
PST - ppublish
SO  - Ann Thorac Surg. 2008 Feb;85(2):488-93. doi: 10.1016/j.athoracsur.2007.09.010.