PMID- 18226776
OWN - NLM
STAT- MEDLINE
DCOM- 20080214
LR  - 20080129
IS  - 1532-8414 (Electronic)
IS  - 1071-9164 (Linking)
VI  - 14
IP  - 1
DP  - 2008 Feb
TI  - Percent predicted value for the 6-minute walk test: using norm-referenced 
      equations to characterize severity in persons with CHF.
PG  - 75-81
LID - 10.1016/j.cardfail.2007.09.005 [doi]
AB  - BACKGROUND: The 6-minute walk test (6MWT) is a widely used measure of functional 
      capacity in patients with chronic heart failure (CHF). Norm-referenced equations 
      that predict the 6-minute walk distance (6MWD) according to age, height, weight, 
      and gender have been proposed for healthy patients. We explored whether these 
      equations apply to CHF patients. METHODS AND RESULTS: The sample consisted of 213 
      patients newly admitted to specialized CHF clinics in Montreal, Canada. Percent 
      predicted value (PPV) for 6MWD was calculated using norm-referenced equations. We 
      explored correlations between different measures: PPV, 6MWD, Minnesota Living 
      with Heart Failure Quality of Life score (MLHF-QOL). We compared severity among 
      different age, gender, and BMI (body mass index) subgroups and assessed 
      consistency using different measures of severity. Mean age was 65.5 years and 
      77.5% were men. Compared with the 6MWD, PPV had a slightly better correlation 
      with MLHF-QOL score (-0.26 versus -0.20), and slightly more predictive power in 
      linear regressions (adjusted r(2) = 6.5% versus 4.2%). When PPV was used to 
      differentiate severity between different age, gender, and BMI subgroups, it 
      consistently led to similar conclusions as the MLHF-QOL score, unlike 6MWD. 
      CONCLUSION: The 6MWD in meters may give misleading results when used as an 
      indicator of severity of CHF condition to compare groups with different sex, age, 
      and BMI distributions. It may be necessary to standardize it using 
      norm-referenced equations.
FAU - Balashov, Konstantin
AU  - Balashov K
AD  - University of Montreal, School of Rehabilitation, Montreal, Canada.
FAU - Feldman, Debbie Ehrmann
AU  - Feldman DE
FAU - Savard, Sylvie
AU  - Savard S
FAU - Houde, Stefanie
AU  - Houde S
FAU - Frenette, Marc
AU  - Frenette M
FAU - Ducharme, Anique
AU  - Ducharme A
FAU - Giannetti, Nadia
AU  - Giannetti N
FAU - Michel, Caroline
AU  - Michel C
FAU - Pilote, Louise
AU  - Pilote L
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Card Fail
JT  - Journal of cardiac failure
JID - 9442138
SB  - IM
MH  - Age Factors
MH  - Aged
MH  - Benchmarking
MH  - Body Mass Index
MH  - Canada
MH  - Exercise Test/*methods
MH  - Exercise Tolerance/physiology
MH  - Female
MH  - Health Status Indicators
MH  - Heart Failure/*diagnosis
MH  - Humans
MH  - Linear Models
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Oxygen Consumption/*physiology
MH  - Prognosis
MH  - Risk Assessment
MH  - Sensitivity and Specificity
MH  - Severity of Illness Index
MH  - Sex Factors
MH  - Time Factors
MH  - Walking
EDAT- 2008/01/30 09:00
MHDA- 2008/02/15 09:00
CRDT- 2008/01/30 09:00
PHST- 2007/04/13 00:00 [received]
PHST- 2007/07/15 00:00 [revised]
PHST- 2007/09/10 00:00 [accepted]
PHST- 2008/01/30 09:00 [pubmed]
PHST- 2008/02/15 09:00 [medline]
PHST- 2008/01/30 09:00 [entrez]
AID - S1071-9164(07)01069-X [pii]
AID - 10.1016/j.cardfail.2007.09.005 [doi]
PST - ppublish
SO  - J Card Fail. 2008 Feb;14(1):75-81. doi: 10.1016/j.cardfail.2007.09.005.