PMID- 18245459
OWN - NLM
STAT- MEDLINE
DCOM- 20080226
LR  - 20111117
IS  - 1538-7445 (Electronic)
IS  - 0008-5472 (Linking)
VI  - 68
IP  - 3
DP  - 2008 Feb 1
TI  - Human leukocyte antigen-G and cancer immunoediting.
PG  - 627-30
LID - 10.1158/0008-5472.CAN-07-2704 [doi]
AB  - Immunosurveillance is an extrinsic mechanism of cancer suppression that 
      eliminates nascent tumors. However, the selection imposed by immunosurveillance 
      can drive tumor evolution and the emergence of clinically apparent neoplasms. 
      Mechanisms of immune escape acquired by less immunogenic variants during this 
      process, termed immunoediting, may contribute significantly to malignant 
      progression. In this review, we summarize the evidence that up-regulation of the 
      nonclassic human leukocyte antigen (HLA) class I molecule HLA-G in tumor cells 
      plays an important role in cancer and immune escape.
FAU - Urosevic, Mirjana
AU  - Urosevic M
AD  - Department of Dermatology, University Hospital Zurich, Zurich, Switzerland. 
      mirjana.urosevic@usz.ch
FAU - Dummer, Reinhard
AU  - Dummer R
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cancer Res
JT  - Cancer research
JID - 2984705R
RN  - 0 (HLA Antigens)
RN  - 0 (HLA-G Antigens)
RN  - 0 (Histocompatibility Antigens Class I)
SB  - IM
MH  - HLA Antigens/*immunology
MH  - HLA-G Antigens
MH  - Histocompatibility Antigens Class I/*immunology
MH  - Humans
MH  - Monitoring, Immunologic
MH  - Neoplasms/*immunology
RF  - 22
EDAT- 2008/02/05 09:00
MHDA- 2008/02/27 09:00
CRDT- 2008/02/05 09:00
PHST- 2008/02/05 09:00 [pubmed]
PHST- 2008/02/27 09:00 [medline]
PHST- 2008/02/05 09:00 [entrez]
AID - 68/3/627 [pii]
AID - 10.1158/0008-5472.CAN-07-2704 [doi]
PST - ppublish
SO  - Cancer Res. 2008 Feb 1;68(3):627-30. doi: 10.1158/0008-5472.CAN-07-2704.