PMID- 18246677
OWN - NLM
STAT- MEDLINE
DCOM- 20090505
LR  - 20161020
IS  - 0255-2922 (Print)
IS  - 0255-2922 (Linking)
VI  - 27
IP  - 4
DP  - 2007 Dec
TI  - Forty-six cases of acute cerebral infarction treated with the combined use of 
      acupuncture and drugs.
PG  - 243-7
AB  - OBJECTIVE: To observe the clinical therapeutic effects of treatment for acute 
      cerebral infarction with the combined use of acupuncture and drugs, and study the 
      therapeutic mechanism. METHODS: 88 cases of acute cerebral infarction were 
      divided randomly into two groups, a treatment group of 46 cases treated with 
      acupuncture, Danshen Zhushe Ye (Saliva Injection) and routine western drugs and a 
      control group of 42 cases treated simply with drugs. The therapeutic effects were 
      evaluated based on the evaluation criteria for damage of the nerve function. 
      Observation was also made on changes in the skull CT images, and in the 
      activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-px), and 
      nitric oxide synthase (NOS) in serums, and levels of malondialdehyde (MDA) and 
      nitric oxide (NO) in serums. RESULTS: After treatment for 15 days, the total 
      effective rate of the treatment group reached 80.43%, while that of the control 
      group was 61.90%, showing significant differences. The effective rate shown by 
      the skull CT images of the treatment group was 51.61%, while that of the control 
      group was 45.16%, showing no significant differences. But as compared with the 
      control group, the activities of SOD and GSH-px in serums were significantly 
      enhanced, and the levels of MDA and NO, and activity of NOS in serums were 
      significantly decreased in the treatment group. CONCLUSION: The prompt 
      acupuncture treatment of acute cerebral infarction can markedly raise the 
      clinical therapeutic effects, improve the activity of SOD and GSH-px in serums, 
      lower down the level of MDA in serum, and markedly decrease NO level and NOS 
      activity in serums.
FAU - Guo, Zhili
AU  - Guo Z
AD  - Nanjing Municipal Hospital of Traditional Chinese Medicine, Nanjing 210001, 
      China.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - J Tradit Chin Med
JT  - Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
JID - 8211546
RN  - 0 (Drugs, Chinese Herbal)
SB  - IM
MH  - *Acupuncture Therapy
MH  - Acute Disease/therapy
MH  - Adult
MH  - Aged
MH  - Cerebral Infarction/*drug therapy/therapy
MH  - Combined Modality Therapy
MH  - Drugs, Chinese Herbal/*administration & dosage
MH  - Female
MH  - Humans
MH  - Injections, Intravenous
MH  - Male
MH  - Middle Aged
EDAT- 2008/02/06 09:00
MHDA- 2009/05/06 09:00
CRDT- 2008/02/06 09:00
PHST- 2008/02/06 09:00 [pubmed]
PHST- 2009/05/06 09:00 [medline]
PHST- 2008/02/06 09:00 [entrez]
PST - ppublish
SO  - J Tradit Chin Med. 2007 Dec;27(4):243-7.